D-dimer levels in the prediction of the degree of intestinal necrosis of etrangulated hernias in rats

被引：9
|
作者：
Zeybek, Nazif [1 ]
Yildiz, Fahrettin [1 ]
Kenar, Levent [2 ]
Peker, Yusuf [1 ]
Kurt, Bu [3 ]
Cetin, Turker [4 ]
Ide, Tayfun [5 ]
Tufan, Turgut [1 ]
机构：
[1] GMMA, Gulhane Sch Med, Dept Gen Surg, TR-06018 Ankara, Turkey
[2] GMMA, Dept Clin Biochem & Med NBC Def, TR-06018 Ankara, Turkey
[3] GMMA, Dept Pathol, TR-06018 Ankara, Turkey
[4] GMMA, Dept Heamatol, TR-06018 Ankara, Turkey
[5] GMMA, Ctr Expt Anim, TR-06018 Ankara, Turkey
来源：
DIGESTIVE DISEASES AND SCIENCES | 2008年 / 53卷 / 07期
关键词：
D-dimer; early diagnosis; leucocyte; strangulated intestinal hernia;
D O I：
10.1007/s10620-007-0088-7
中图分类号：
R57 [消化系及腹部疾病];
学科分类号：
摘要：
Purpose The aim of this study was to investigate the time-dependent relation between plasma D-dimer levels and the degree of intestinal necrosis and to compare these parameters with leukocyte counts in an experimental etrangulated hernia model in rats. Results When the duration of intestinal ischemia was prolonged, serum D-dimer levels increased relative to the control group, with the difference being statistically significant at hour 2 (P = 0.027). In contrast, leukocyte counts in the 2- and 4-h strangulation group were higher that those of the control group, but the difference was not statistically significant (P = 0.625 and P = 0.846, respectively). However, in the 6-h strangulation group the levels of leukocytes were significantly higher that those of the control group (P = 0.015). Conclusion Serum D-dimer measurements may be used as a more valuable diagnostic parameter than leukocyte count in the early diagnosis of intestinal ischemia, including strangulated hernia.
引用
收藏
页码：1832 / 1836
页数：5
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