Production of Fumaric Acid by Rhizopus arrhizus NRRL 1526: A Simple Production Medium and the Kinetic Modelling of the Bioprocess

被引：8

作者：

Martin-Dominguez, Victor ^{[1
]}

Cabrera, Paula I. Aleman ^{[1
]}

Eidt, Laslo ^{[2
]}

Pruesse, Ulf ^{[2
]}

Kuenz, Anja ^{[2
]}

Ladero, Miguel ^{[1
]}

Santos, Victoria E. ^{[1
]}

机构：

[1] Univ Complutense Madrid, Chem Sci Sch, Mat & Chem Engn Dept, FQPIMA Grp, Madrid 28040, Spain

[2] Thunen Inst Agr Technol, D-38116 Braunschweig, Germany

来源：

FERMENTATION-BASEL | 2022年 / 8卷 / 02期

关键词：

fumaric acid; Rhizopus arrhizus; kinetic modelling; fermentation; LASER REFLECTANCE; ORYZAE; FERMENTATION; CARBONATE; STRATEGY; WASTE;

D O I：

10.3390/fermentation8020064

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

Fumaric acid is a promising monomer to obtain biomass-based polyesters and polyamides, and it is mainly produced by fungi of the Rhizopus genus in medium to high titters. The use of glucose, a main component of starchy and cellulosic food waste, as carbon source, together with a low-nitrogen source concentration, is a promising route to reduce process costs. In this work, the effects of nitrogen and carbonate sources on Rhizopus arrhizus NRRL 1526 morphology and fumaric acid productivity were analysed, simplifying the traditional production broth composition. Moreover, a non-structured, non-segregated kinetic model was proposed and fitted to concentration data of all relevant components obtained in batches performed in triplicate with the selected production broth at 34 degrees C and 200 rpm in an orbital shaker.

引用

页数：18

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