Neonatal Tetanus in Vietnam: Comprehensive Intensive Care Support Improves Mortality

被引：12

作者：

Trieu, Huynh T. ^{[1
]}

Lubis, Inke N. ^{[2
]}

Qui, Phan T. ^{[1
]}

Yen, Lam M. ^{[1
]}

Wills, Bridget ^{[3
,4
]}

Thwaites, C. Louise ^{[3
,4
]}

Sabanathan, Saraswathy ^{[3
,4
]}

机构：

[1] Hosp Trop Dis, 764 Vo Van Kiet,Dist 5, Ho Chi Minh City, Vietnam

[2] Univ North Sumatera, Jl Dr Mansur 5, Medan, Indonesia

[3] Hosp Trop Dis, Oxford Univ Clin Res Unit, Ho Chi Minh City, Vietnam

[4] Univ Oxford, Nuffield Dept Med, Ctr Trop Med & Global Hlth, Oxford OX1 2JD, England

来源：

JOURNAL OF THE PEDIATRIC INFECTIOUS DISEASES SOCIETY | 2016年 / 5卷 / 02期

基金：

英国惠康基金;

关键词：

autonomic dysfunction; magnesium sulfate; neonatal tetanus; MAGNESIUM-SULFATE; METAANALYSIS; DYSFUNCTION; PROGNOSIS; INFANTS;

D O I：

10.1093/jpids/piv059

中图分类号：

R51 [传染病];

学科分类号：

100401 ;

摘要：

We report a 66% reduction in neonatal tetanus mortality after introducing a new management bundle integrating antibiotic therapy, muscle relaxation and invasive monitoring. The latter allowed rapid detection of autonomic instability which was treated with magnesium sulphate. This is the first report of its use in neonatal tetanus.

引用

页码：227 / 230

页数：4

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