Smear cytological features of large cell neuroendocrine carcinoma of the uterine cervix in pregnancy: A case report and review of the literature

被引:1
作者
Erdem, Busra Ersan [1 ]
Cigdem, Vural [1 ]
Sener, Gezer [2 ]
Bahar, Muezzinoglu [1 ]
Kursat, Yildiz Demir [1 ]
Izzet, Yucesoy [2 ]
机构
[1] Kocaeli Univ, Dept Pathol, Fac Med, Kocaeli, Turkey
[2] Kocaeli Univ, Dept Obstet & Gynecol, Fac Med, Kocaeli, Turkey
关键词
cytology; large-cell neuroendocrine carcinoma; smear; uterine cervix; ADENOCARCINOMA; TUMORS;
D O I
10.1002/dc.24106
中图分类号
R446 [实验室诊断]; R-33 [实验医学、医学实验];
学科分类号
1001 ;
摘要
Large-cell neuroendocrine carcinoma (LCNEC) of the uterine cervix is a rare aggressive tumor. The examination of a cervicovaginal smear from a 31-year-old patient diagnosed with LCNEC after a cervical polypectomy during the 32nd week of pregnancy was carried out. The observed atypical cells had large cytoplasm, increased nucleus: cytoplasm ratio with the nucleus containing coarse, dispersed chromatin, and were arranged in a pseudorosette formation, which all confirmed the diagnosis. In addition, adenocarcinoma in situ (AIS) was determined in the histopathological examination of the subsequent hysterectomy material. Given the rarity of this condition, we present and discuss the case herein.
引用
收藏
页码:137 / 141
页数:5
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