Salvia nemorosa L.: A novel source of bioactive agents with functional connections

被引：59

作者：

Bahadori, Mir Babak ^{[1
]}

Asghari, Behvar ^{[2
]}

Dinparast, Leila ^{[3
]}

Zengin, Gokhan ^{[4
]}

Sarikurkcu, Cengiz ^{[5
]}

Abbas-Mohammadi, Mandi ^{[6
]}

Bahadori, Shahram ^{[7
]}

机构：

[1] Tabriz Univ Med Sci, Res Ctr Pharmaceut Nanotechnol, Tabriz, Iran

[2] Imam Khomeini Int Univ, Fac Engn & Technol, Dept Plant Prod & Breeding Engn, Qazvin, Iran

[3] Tabriz Univ Med Sci, Biotechnol Res Ctr, Tabriz, Iran

[4] Selcuk Univ, Fac Sci, Dept Biol, Konya, Turkey

[5] Suleyman Demirel Univ, Dept Analyt Chem, Fac Pharm, Isparta, Turkey

[6] Shahid Beheshti Univ, Med Plants & Drugs Res Inst, Dept Phytochem, Tehran, Iran

[7] Urmia Univ Med Sci, Fac Pharm, Dept Pharmacognosy, Orumiyeh, Iran

来源：

LWT-FOOD SCIENCE AND TECHNOLOGY | 2017年 / 75卷

关键词：

Salvia; Acetylcholinesterase; Diabetes mellitus; Alzheimer's disease; Phenolics; ESSENTIAL-OIL COMPOSITION; IN-VITRO ANTIOXIDANT; ANTIPROLIFERATIVE ACTIVITIES; ANTIMICROBIAL ACTIVITIES; INHIBITORY-ACTIVITY; DIABETES-MELLITUS; PHENOLIC CONTENTS; URMIENSIS BUNGE; ROSMARINIC ACID; CONSTITUENTS;

D O I：

10.1016/j.lwt.2016.08.048

中图分类号：

TS2 [食品工业];

学科分类号：

0832 ;

摘要：

Salvia species are used as food and medicinal plants all around the world. In this study, chemical composition and antimicrobial, toxicity, antioxidant, and enzyme inhibitory activity of Salvia nemorosa were evaluated. Phenolic components were characterized by the HPLC-DAD and 11 components were identified, in which rosmarinic acid was detected as the major compound (7584 mu g/g extract). Sixteen volatile components were determined in both leaves and flowers essential oils. Oxygenated sesquiterpenes were the major components. Methanolic extract showed the highest total phenolic and flavonoid contents (294 mg GAE/g and 117 mg QE/g extract, respectively) and the strongest DPPH radical scavenging activity (IC50: 82 mu g/mL). Plant samples showed moderate to high aldehyde oxidase, xanthine oxidase, acetylcholinesterase, and alpha-glucosidase inhibitory activity and moderate cytotoxicity. Also, EOs exhibited great antimicrobial potential (IZ: 8.8-33.7 mm). Our findings indicated that S. nemorosa may be useful for novel applications in functional food and pharmaceutical industries. (C) 2016 Elsevier Ltd. All rights reserved.

引用

页码：42 / 50

页数：9

共 58 条

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