Role of Micronutrients in Skin Health and Function

被引:49
作者
Park, Kyungho [1 ]
机构
[1] Univ Calif San Francisco, VA Med Ctr, NCIRE, Dept Dermatol, San Francisco, CA 94158 USA
关键词
Skin disease; Skin function; Micronutrient; Therapeutic agent; Cosmetic ingredient; INDUCED OXIDATIVE DAMAGE; BLOCKING-AGENTS RAMBAS; VITAMIN-E-DEFICIENCY; CULTURED HUMAN SKIN; RETINOIC ACID; ULTRAVIOLET-RADIATION; IN-VIVO; KERATINOCYTE PROLIFERATION; PERMEABILITY BARRIER; ANTIOXIDANT NETWORK;
D O I
10.4062/biomolther.2015.003
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Skin is the first line of defense for protecting our bodies against external perturbations, including ultraviolet (UV) irradiation, mechanical/chemical stress, and bacterial infection. Nutrition is one of many factors required for the maintenance of overall skin health. An impaired nutritional status alters the structural integrity and biological function of skin, resulting in an abnormal skin barrier. In particular, the importance of micronutrients (such as certain vitamins and minerals) for skin health has been highlighted in cell culture, animal, and clinical studies. These micronutrients are employed not only as active compounds in therapeutic agents for treating certain skin diseases, but also as ingredients in cosmetic products. Here, the author describes the barrier function of the skin and the general nutritional requirements for skin health. The goal of this review is to discuss the potential roles and current knowledge of selected micronutrients in skin health and function.
引用
收藏
页码:207 / 217
页数:11
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