Manganese-Catalyzed [4+2] Annulation of N-H Amidines with Vinylene Carbonate via C-H Activation

被引：33

作者：

Li, Yudong ^{[1
,2
]}

Wang, Huan ^{[1
,2
]}

Li, Ying ^{[1
]}

Li, Yang ^{[1
,2
]}

Sun, Yuxia ^{[1
]}

Xia, Chungu ^{[1
]}

Li, Yuehui ^{[1
]}

机构：

[1] Chinese Acad Sci, Ctr Excellence Mol Synth, Suzhou Res Inst LICP, Lanzhou Inst Chem Phys LICP,State Key Lab Oxo Syn, Lanzhou 730000, Peoples R China

[2] Univ Chinese Acad Sci, Beijing 100049, Peoples R China

来源：

JOURNAL OF ORGANIC CHEMISTRY | 2021年 / 86卷 / 24期

关键词：

BOND ACTIVATION; ALKYNES; ACCESS; ALKENYLATION; ISOQUINOLINE; IMIDAMIDES; ARYLATION; INDOLES; FUNCTIONALIZATION; DERIVATIVES;

D O I：

10.1021/acs.joc.1c02473

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Manganese-catalyzed C-H bond functionalization of aryl amidines for the synthesis of 1-aminoisoquinolines in the presence of vinylene carbonate has been developed. The reaction features a broad substrate scope and proceeds under mild reaction conditions with only the carbonate anion as the byproduct.

引用

页码：18204 / 18210

页数：7

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