Manganese-Catalyzed [4+2] Annulation of N-H Amidines with Vinylene Carbonate via C-H Activation

被引：33
|
作者：
Li, Yudong [1 ,2 ]
Wang, Huan [1 ,2 ]
Li, Ying [1 ]
Li, Yang [1 ,2 ]
Sun, Yuxia [1 ]
Xia, Chungu [1 ]
Li, Yuehui [1 ]
机构：
[1] Chinese Acad Sci, Ctr Excellence Mol Synth, Suzhou Res Inst LICP, Lanzhou Inst Chem Phys LICP,State Key Lab Oxo Syn, Lanzhou 730000, Peoples R China
[2] Univ Chinese Acad Sci, Beijing 100049, Peoples R China
来源：
JOURNAL OF ORGANIC CHEMISTRY | 2021年 / 86卷 / 24期
关键词：
BOND ACTIVATION; ALKYNES; ACCESS; ALKENYLATION; ISOQUINOLINE; IMIDAMIDES; ARYLATION; INDOLES; FUNCTIONALIZATION; DERIVATIVES;
D O I：
10.1021/acs.joc.1c02473
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
Manganese-catalyzed C-H bond functionalization of aryl amidines for the synthesis of 1-aminoisoquinolines in the presence of vinylene carbonate has been developed. The reaction features a broad substrate scope and proceeds under mild reaction conditions with only the carbonate anion as the byproduct.
引用
收藏
页码：18204 / 18210
页数：7
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