Extracts of black and brown rice powders improve hepatic lipid accumulation via the activation of PPARα in obese and diabetic model mice

被引：12
|
作者：
Felix, Angelina D. R. [1 ,2 ]
Takahashi, Nobuyuki [1 ]
Takahashi, Mami [1 ]
Katsumata-Tsuboi, Rie [1 ]
Satoh, Ryo [1 ]
Hui, Teoh Soon [3 ]
Miyajima, Katsuhiro [3 ]
Nakae, Dai [3 ]
Inoue, Hirofumi [1 ]
Uehara, Mariko [1 ]
机构：
[1] Tokyo Univ Agr, Fac Appl Biosci, Dept Nutr Sci & Food Safety, Lab Physiol & Metab, Tokyo, Japan
[2] Univ Philippines, Los Banos Coll Human Ecol, Inst Human Nutr & Food, Laguna, Philippines
[3] Tokyo Univ Agr, Fac Appl Biosci, Dept Nutr Sci & Food Safety, Lab Food Safety Assessment Sci, Tokyo, Japan
来源：
BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY | 2017年 / 81卷 / 11期
关键词：
rice powder; liver; lipid metabolism; fatty acid oxidation; PPAR; METABOLISM;
D O I：
10.1080/09168451.2017.1372178
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
Rice powder extract (RPE) from black and brown rice (Oryza sativa L. indica) improves hepatic lipid accumulation in obese and diabetic model mice via peroxisomal fatty acid oxidation. RPE showed PPAR alpha agonistic activity which did not differ between black and brown RPE despite a higher anthocyanin content in black RPE.
引用
收藏
页码：2209 / 2211
页数：3
相关论文
共 10 条
  • [1] Black rice bran improved lipid metabolism in hyperlipidemia mice via steroid hormone biosynthesis and PPAR signaling pathway
    Li, Xiang
    Tan, Kevin Shyong Wei
    Wang, Li
    JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2025, 262
  • [2] Dill seed extract improves abnormalities in lipid metabolism through peroxisome proliferator-activated receptor-α (PPAR-α) activation in diabetic obese mice
    Takahashi, Nobuyuki
    Yao, Lan
    Kim, Minji
    Sasako, Hiroshi
    Aoyagi, Morihiro
    Shono, Jinji
    Tsuge, Nobuaki
    Goto, Tsuyoshi
    Kawada, Teruo
    MOLECULAR NUTRITION & FOOD RESEARCH, 2013, 57 (07) : 1295 - 1299
  • [3] Flax oil-mediated activation of PPAR-γ correlates with reduction of hepatic lipid accumulation in obese spontaneously hypertensive/NDmcr-cp rats, a model of the metabolic syndrome
    Chechi, Kanta
    Yasui, Naomi
    Ikeda, Katsumi
    Yamori, Yukio
    Cheema, Sukhinder K.
    BRITISH JOURNAL OF NUTRITION, 2010, 104 (09) : 1313 - 1321
  • [4] Exogenous natural EPA-enriched phosphatidylcholine and phosphatidylethanolamine ameliorate lipid accumulation and insulin resistance via activation of PPARα/γ in mice
    Tian, Yingying
    Liu, Yanjun
    Xue, Changhu
    Wang, Jingfeng
    Wang, Yuming
    Xu, Jie
    Li, Zhaojie
    FOOD & FUNCTION, 2020, 11 (09) : 8248 - 8258
  • [5] Ellagic acid improves hepatic steatosis and serum lipid composition through reduction of serum resistin levels and transcriptional activation of hepatic ppara in obese, diabetic KK-Ay mice
    Yoshimura, Yukihiro
    Nishii, Saori
    Zaima, Nobuhiro
    Moriyarha, Tatsuya
    Kawamura, Yukio
    BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2013, 434 (03) : 486 - 491
  • [6] Astaxanthin reduces hepatic lipid accumulations in high-fat-fed C57BL/6J mice via activation of peroxisome proliferator-activated receptor (PPAR) alpha and inhibition of PPAR gamma and Akt
    Jia, Yaoyao
    Wu, Chunyan
    Kim, Jiyoung
    Kim, Bobae
    Lee, Sung-Joon
    JOURNAL OF NUTRITIONAL BIOCHEMISTRY, 2016, 28 : 9 - 18
  • [7] Anti-diabetic activity of chemically profiled green tea and black tea extracts in a type 2 diabetes mice model via different mechanisms
    Tang, Wenping
    Li, Shiming
    Liu, Yue
    Huang, Mou-Tuan
    Ho, Chi-Tang
    JOURNAL OF FUNCTIONAL FOODS, 2013, 5 (04) : 1784 - 1793
  • [8] Brown rice inhibits development of non-alcoholic fatty liver disease in obese Zucker (fa/fa) rats by increasing VLDL-secretion and lipid oxidation via activation of retinoic acid synthesis
    Yamamoto, Yuji
    Suzuki, Tsukasa
    Matsumoto, Yu
    Kobayashi, Ken-Ichi
    Inoue, Jun
    ANNALS OF NUTRITION AND METABOLISM, 2023, 79 : 411 - 412
  • [9] Hovenia Dulcis Extract Reduces Lipid Accumulation in Oleic Acid-Induced Steatosis of Hep G2 Cells via Activation of AMPK and PPARα/CPT-1 Pathway and in Acute Hyperlipidemia Mouse Model
    Kim, Bonglee
    Woo, Moon-Jea
    Park, Chul-Soo
    Lee, Sang-Hun
    Kim, Jin-Soo
    Kim, Boim
    An, Seho
    Kim, Sung-Hoon
    PHYTOTHERAPY RESEARCH, 2017, 31 (01) : 132 - 139
  • [10] Lemon Balm Extract ALS-L1023 Regulates Obesity and Improves Insulin Sensitivity via Activation of Hepatic PPARα in High-Fat Diet-Fed Obese C57BL/6J Mice
    Lee, Dongju
    Shin, Yujin
    Roh, Jong Seong
    Ahn, Jiwon
    Jeoong, Sunhyo
    Shin, Soon Shik
    Yoon, Michung
    INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2020, 21 (12) : 1 - 17
1