Synthesis and characterization of novel metabotropic glutamate receptor 2/3 (mGluR2/3) positive allosteric modulator (PAM)

被引：0

作者：

Branski, Piotr ^{[1
]}

Staron, Jakub ^{[2
]}

Bugno, Ryszard ^{[2
]}

Wieronska, Joanna ^{[1
]}

Bojarski, Andrzej ^{[2
]}

Burnat, Grzegorz

Palucha-Poniewiera, Agnieszka ^{[1
]}

Pilc, Andrzej ^{[1
]}

机构：

[1] Polish Acad Sci, Inst Pharmacol, Dept Neurobiol, PL-31343 Krakow, Poland

[2] Polish Acad Sci, Inst Pharmacol, Dept Med Chem, PL-31343 Krakow, Poland

来源：

PHARMACOLOGICAL REPORTS | 2011年 / 63卷 / 02期

关键词：

D O I：

暂无

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

引用

页码：577 / 577

页数：1

共 50 条

[31] Preclinical profile of a novel metabotropic glutamate receptor 5 positive allosteric modulator [J].

Spear, Nathan ;

Gadient, Reto A. ;

Wilkins, Deidre E. ;

Do, MyLinh ;

Smith, Jeffrey S. ;

Zeller, Kim L. ;

Schroeder, Patricia ;

Zhang, Minli ;

Arora, Jalaj ;

Chhajlani, Vijay .

EUROPEAN JOURNAL OF PHARMACOLOGY, 2011, 659 (2-3) :146-154

[32] Design, synthesis, and evaluation of novel biphenyl indanone-A (BINA) derivatives that are metabotropic glutamate receptor subtype-2 (mGluR2) positive allosteric modulators (PAMs): Initial refinement of SAR [J].

Sidique, Shyama ;

Sheffler, Douglas ;

Herath, Ananda ;

Dahl, Russell ;

Yang, Li ;

Semenova, Svetlana ;

Zin, Xinchun ;

Markou, Athina ;

Conn, Jeffrey P. ;

Cosford, Nicholas D. P. .

ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2010, 239

[33] IMMUNOHISTOCHEMICAL LOCALIZATION OF METABOTROPIC GLUTAMATE RECEPTORS, MGLUR2 AND MGLUR3, IN RAT CEREBELLAR CORTEX [J].

OHISHI, H ;

OGAWAMEGURO, R ;

SHIGEMOTO, R ;

KANEKO, T ;

NAKANISHI, S ;

MIZUNO, N .

NEURON, 1994, 13 (01) :55-66

[34] AZD8529-An mGluR2 Positive Allosteric Modulator for the Treatment of Schizophrenia [J].

Cross, Alan .

NEUROPSYCHOPHARMACOLOGY, 2013, 38 :S25-S25

[35] Roles of presynaptic mGluR2 metabotropic glutamate receptor in hippocampal synaptic plasticity [J].

Yokoi, M ;

Nakanishi, S .

GENE TARGETING AND NEW DEVELOPMENTS IN NEUROBIOLOGY, 1996, (19) :115-123

[36] Unipolar brush cells in the human cochlear nuclei identified by their expression of a metabotropic glutamate receptor (mGluR2/3) [J].

Spatz, WB .

NEUROSCIENCE LETTERS, 2001, 316 (03) :161-164

[37] Discovery of LY2607540: A novel and selective mGluR2 positive allosteric modulator (PAM) demonstrates activity in animal models of anxiety and depression [J].

Khilevich, Albert ;

Mayhugh, Daniel R. ;

Hay, David A. ;

Zhang, Deyi ;

Liu, Bin ;

Svensson, Kjell A. ;

Falcone, Julie F. ;

Heinz, Beverly A. ;

Wang, Xushan ;

Witkin, Jeff M. ;

Rassmussen, Kurt ;

Rorick-Kehn, Linda ;

Benvenga, Mark J. ;

Li, Xia ;

Hart, John C. ;

Chaney, Stephen ;

Catlow, John T. ;

Swanson, Steve ;

Schkeryantz, Jeffrey M. .

ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2013, 246

[38] LY2607540 (THIIC): A Novel, Brain Penetrant, Positive Allosteric Modulator of the Metabotropic Glutamate Receptor 2 [J].

Schkeryantz, J. ;

Svensson, K. ;

Kehn, L. Rorick ;

Fell, M. ;

Witkin, J. M. ;

Felder, C. ;

Mayhugh, D. ;

Khilevich, A. ;

Swanson, S. ;

Catlow, J. ;

Heinz, B. ;

Wang, Xushan .

CURRENT NEUROPHARMACOLOGY, 2011, 9 :57-58

[39] Neurophysiologic and Antipsychotic Profiles of TASP0433864, a Novel Positive Allosteric Modulator of Metabotropic Glutamate 2 Receptor [J].

Hiyoshi, Tetsuaki ;

Marumo, Toshiyuki ;

Hikichi, Hirohiko ;

Tomishima, Yasumitsu ;

Urabe, Hiroki ;

Tamita, Tomoko ;

Iida, Izumi ;

Yasuhara, Akito ;

Karasawa, Jun-ichi ;

Chaki, Shigeyuki .

JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS, 2014, 351 (03) :642-653

[40] Metabotropic Glutamate Receptor 2/3 (mGluR2/3) Activation Suppresses TRPV1 Sensitization in Mouse, But Not Human, Sensory Neurons [J].

Sheahan, Tayler D. ;

Valtcheva, Manouela V. ;

Mcllvried, Lisa A. ;

Pullen, Melanie Y. ;

Baranger, David A. A. ;

Gereau, Robert W. .

ENEURO, 2018, 5 (02)

← 1 2 3 4 5 →