A novel feature of microsatellites in plants: a distribution gradient along the direction of transcription

被引：86

作者：

Fujimori, S

Washio, T ^{[1
]}

Higo, K

Ohtomo, Y

Murakami, K

Matsubara, K

Kawai, J

Carninci, P

Hayashizaki, Y

Kikuchi, S

Tomita, M

机构：

[1] Keio Univ, Inst Adv Biosci, Tsuruoka, Yamagata 9970035, Japan

[2] Natl Inst Agrobiol Sci, Tsukuba, Ibaraki 3050062, Japan

[3] RIKEN, Genom Sci Ctr, Lab Genome Explorat Res Grp, Yokohama, Kanagawa 2300045, Japan

[4] Keio Univ, Dept Environm Informat, Fujisawa, Kanagawa 2528520, Japan

来源：

FEBS LETTERS | 2003年 / 554卷 / 1-2期

关键词：

microsatellite; tandem repeat; full-length cDNA; transcribed region; transcriptional regulation;

D O I：

10.1016/S0014-5793(03)01041-X

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

A computer-based analysis was conducted to assess the characteristics of microsatellites in transcribed regions of rice and Arabidopsis. In addition, two mammals were simultaneously analyzed for a comparative analysis. Our analyses confirmed a novel plant-specific feature in which there is a gradient in microsatellite density along the direction of transcription. It was also confirmed that pyrimidine-rich microsatellites are found intensively near the transcription start sites, specifically in the two plants, but not in the mammals. Our results suggest that microsatellites located at high frequency in the 5'-flanking regions of plant genes can potentially act as factors in regulating gene expression. (C) 2003 Federation of European Biochemical Societies. Published by Elsevier B.V. All rights reserved.

引用

页码：17 / 22

页数：6

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