Rapid Responsive Behaviors of the Dual Stimuli-Sensitive Poly(DEA-co-DMAEMA) Hydrogel via Comb-Type Grafted Polymeriziation

被引：18
作者：
Chen, Jun [1 ,2 ,3 ]
Dai, Peipei [4 ]
Liu, Mingzhu [1 ,2 ]
机构：
[1] Lanzhou Univ, State Key Lab Appl Organ Chem, Lanzhou 730000, Peoples R China
[2] Lanzhou Univ, Dept Chem, Lanzhou 730000, Peoples R China
[3] Fudan Univ, Dept Macromol Sci, Key Lab Mol Engn Polymers, Shanghai 200433, Peoples R China
[4] Suzhou Polytech Inst Agr, Suzhou, Peoples R China
来源：
INTERNATIONAL JOURNAL OF POLYMERIC MATERIALS | 2012年 / 61卷 / 1-4期
基金：
中国国家自然科学基金;
关键词：
graft; hydrogel; pH-sensitive; rapid response; thermosensitive; POLY(N-ISOPROPYLACRYLAMIDE) HYDROGELS; THERMOSENSITIVE PNIPAAM; DESWELLING RESPONSE; RADIATION SYNTHESIS; DRUG-DELIVERY; CHAIN-LENGTH; PH; RELEASE; ACID; CELLULOSE;
D O I：
10.1080/00914037.2011.557805
中图分类号：
O63 [高分子化学（高聚物）];
学科分类号：
070305 ; 080501 ; 081704 ;
摘要：
The dual-sensitive, comb-type grafted hydrogels were synthesized by grafting polymeric chains with freely mobile ends, which were composed of both N,N-diethylacrylamide (DEA) and (2-dimethylamino) ethyl methacrylate (DMAEMA), onto the backbone of crosslinked poly(DEA-co-DMAEMA) networks. The structure of the poly(DEA-co-DMAEMA) macromonomer was characterized by Nuclear Magnetic Resonance (H-1 NMR) and Fourier transform infrared spectroscopy (FTIR). The effects of the feed components, temperature, and pH on the swelling behavior of the hydrogels were studied. With the increase of the poly(DEA-co-DMAEMA) macromonomer content, the thermo- and pH-sensitivity of the hydrogels improved. The G-PDD hydrogels exhibited improved thermo- and pH-sensitive characteristics, such as faster deswelling and reswelling rates and great oscillating deswelling/swelling behavior, and the level of improvement depended on the poly(DEA-co-DMAEMA) macromonomer content. The proposed dual thermo- and pH-sensitive, comb-type grafted poly(DEA-co-DMAEMA) hydrogel has various potential applications.
引用
收藏
页码：177 / 198
页数：22
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