Prevention of coronary heart disease - role of body weight

被引：0
作者：
Wirth, A
Gohlke, H
机构：
[1] Teutoburger Wald Klin, D-49214 Bad Rothenfelde, Germany
[2] Klin Kardiol 2, Herzzentrum, Bad Krozingen, Germany
来源：
ZEITSCHRIFT FUR KARDIOLOGIE | 2005年 / 94卷
关键词：
obesity; risk factors; coronary heart disease; atherosclerosis;
D O I：
10.1007/s00392-005-1305-z
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
The prevalence of obesity has increased considerably in recent years; only one third of our population displays a desirable, healthy weight. Persons with increased body fat mass are in a constant pro-inflammatory and pro-thrombotic condition; in addition they are often insulin-resistant und show cardiovascular risk factors. Therefore, obesity induces the development of atherosclerosis as an independent risk factor as well as a promoter for other risk factors. In addition, congestive heart failure is more frequent in obese subjects. By reducing body weight with a decrease of predominantly visceral fat all risk factors are improved as well as endothelial function. Effects on coronary atherosclerosis and congestive heart disease are until now insufficiently investigated.
引用
收藏
页码：22 / 29
页数：8
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