Micropapillary Lung Cancer with Breast Metastasis Simulating Primary Breast Cancer due to Architectural Distortion on Images

被引：14

作者：

Ko, Kyungran ^{[1
]}

Ro, Jae Yoon ^{[2
,4
]}

Hong, Eun Kyung ^{[2
]}

Lee, Seeyeon ^{[3
]}

机构：

[1] Natl Canc Ctr, Ctr Breast Canc, Dept Diagnost Radiol, Goyang 410769, South Korea

[2] Natl Canc Ctr, Ctr Breast Canc, Dept Pathol, Goyang 410769, South Korea

[3] Natl Canc Ctr, Ctr Breast Canc, Dept Surg, Goyang 410769, South Korea

[4] Cornell Univ, Weill Med Coll, Methodist Hosp, Dept Pathol, Houston, TX USA

来源：

KOREAN JOURNAL OF RADIOLOGY | 2012年 / 13卷 / 02期

关键词：

Metastasis; Breast images; Lung cancer; Micropapillary carcinoma; ADENOCARCINOMA; CARCINOMAS; EXPRESSION; COMPONENT;

D O I：

10.3348/kjr.2012.13.2.249

中图分类号：

R8 [特种医学]; R445 [影像诊断学];

学科分类号：

1002 ; 100207 ; 1009 ;

摘要：

A 47-year-old Korean woman with right middle lobe Lung adenocarcinoma, malignant pleural effusion, and multiple lymph node and bone metastases, after three months of Lung cancer diagnosis, presented with a palpable right breast mass. Images of the right breast demonstrated architectural distortion that strongly suggested primary breast cancer. Breast biopsy revealed metastatic lung cancer with a negative result for estrogen receptor (ER), progesterone receptor (PR) and mammaglobin, and a positive result for thyroid transcription factor-1 (TTF-1). We present a case of breast metastasis from a case of lung cancer with an extensive micropapillary component, which was initially misinterpreted as a primary breast cancer due to unusual image findings with architectural distortion.

引用

页码：249 / 253

页数：5

共 14 条

[1] Invasive Micropapillary Carcinoma of the Breast: Mammographic, Sonographic, and MRI Features [J].

Adrada, Beatriz ;

Arribas, Elsa ;

Gilcrease, Michael ;

Yang, Wei Tse .

AMERICAN JOURNAL OF ROENTGENOLOGY, 2009, 193 (01) :W58-W63

[2] Micropapillary component in lung adenocarcinoma -: A distinctive histologic feature with possible prognostic significance [J].

Amin, MB ;

Tamboli, P ;

Merchant, SH ;

Ordóñez, NG ;

Ro, J ;

Ayala, AG ;

Ro, JY .

AMERICAN JOURNAL OF SURGICAL PATHOLOGY, 2002, 26 (03) :358-364

[3] Mammaglobin vs GCDFP-15 - An immunohistologic validation survey for sensitivity and specificity [J].

Bhargava, Rohit ;

Beriwal, Sushil ;

Dabbs, David J. .

AMERICAN JOURNAL OF CLINICAL PATHOLOGY, 2007, 127 (01) :103-113

[4] Immunohistochemical Expression of Estrogen Receptor in Adenocarcinomas of the Lung The Antibody Factor [J].

Gomez-Fernandez, Carmen ;

Mejias, Aldo ;

Walker, Gail ;

Nadji, Mehrdad .

APPLIED IMMUNOHISTOCHEMISTRY & MOLECULAR MORPHOLOGY, 2010, 18 (02) :137-141

[5]

HAJDU SI, 1972, CANCER-AM CANCER SOC, V29, P1691, DOI 10.1002/1097-0142(197206)29:6<1691::AID-CNCR2820290637>3.0.CO

[6]

2-4

[7] Metastatic tumors to the breast: Mammographic and ultrasonographic findings [J].

Lee, SH ;

Park, JM ;

Kook, SH ;

Han, BK ;

Moon, WK .

JOURNAL OF ULTRASOUND IN MEDICINE, 2000, 19 (04) :257-262

[8] Lung adenocarcinomas with micropapillary components [J].

Maeda R. ;

Isowa N. ;

Onuma H. ;

Miura H. ;

Harada T. ;

Touge H. ;

Tokuyasu H. ;

Kawasaki Y. .

General Thoracic and Cardiovascular Surgery, 2009, 57 (10) :534-539

[9] Metastasis to the breast from an adenocarcinoma of the lung with extensive micropapillary component: a case report and review of the literature [J].

Maounis, Nicoletta ;

Chorti, Maria ;

Legaki, Stella ;

Ellina, Eleni ;

Emmanouilidou, Aphrodite ;

Demonakou, Maria ;

Tsiafaki, Xanthi .

DIAGNOSTIC PATHOLOGY, 2010, 5

[10]

Masmoudi A, 2003, ANTICANCER RES, V23, P1825

← 1 2 →