Adult and fetal wound healing

被引：95

作者：

Hantash, Basil M. ^{[1
]}

Zhao, Longmei ^{[1
]}

Knowles, Joseph A. ^{[1
]}

Lorenz, H. Peter ^{[1
]}

机构：

[1] Stanford Univ, Sch Med, Dept Surg, Div Plast Surg, Stanford, CA 94305 USA

来源：

FRONTIERS IN BIOSCIENCE-LANDMARK | 2008年 / 13卷

关键词：

wound healing; scarless; fibroblast; review;

D O I：

10.2741/2559

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Mammalian wound healing is an intricate process involving the coordinated interaction of a variety of tissue types and cellular lineages. This is governed by a complex array of physical, biological and chemical signals. In adult tissue, the successful completion of wound healing inevitably results in the formation of scar. However, animal studies of embryonic tissue have shown that early gestation fetal wounds heal with complete restoration of tissue structure and function. The exact mechanisms underlying scarless healing in the fetus remain to be elucidated.

引用

页码：51 / 61

页数：11

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