Irbesartan in the regression of left ventricular hypertrophy

被引：0
|
作者：
Malmqvist, K [1 ]
Kahan, T [1 ]
Edner, M [1 ]
Held, C [1 ]
Osbakken, M [1 ]
机构：
[1] Karolinska Inst, Danderyd Hosp, Div Internal Med, S-18288 Danderyd, Sweden
来源：
XIII WORLD CONGRESS OF CARDIOLOGY: FREE PAPERS | 1998年
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D O I：
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中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
Left ventricular hypertrophy (LVH) is a major independent risk factor for cardiovascular disease and a significant independent predictor of mortality (Sullivan et ai, 1993). The effects of irbesartan (IRBE) on the regression of left ventricular hypertrophy (LVH) were compared to those of atenolol (ATN) in a double-blind, 48-week study. Despite similar reductions in blood pressure (BP), LVH regressed sooner and to a greater degree with IRBE compared with ATN. Thus, IRBE produced superior end organ protection with better tolerability.
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页码：427 / 431
页数：5
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