Bioactive natural products in COVID-19 therapy

被引：53
作者：
Wang, Zhonglei [1 ,2 ]
Wang, Ning [3 ]
Yang, Liyan [4 ]
Song, Xian-qing [3 ]
机构：
[1] Qufu Normal Univ, Key Lab Green Nat Prod & Pharmaceut Intermediates, Sch Chem & Chem Engn, Qufu, Peoples R China
[2] Tsinghua Univ, Sch Pharmaceut Sci, Beijing, Peoples R China
[3] Ningbo Fourth Hosp, Gen Surg Dept, Xiangshan, Peoples R China
[4] Qufu Normal Univ, Sch Phys & Phys Engn, Qufu, Peoples R China
来源：
FRONTIERS IN PHARMACOLOGY | 2022年 / 13卷
关键词：
natural products; COVID-19; SARS-CoV-2; cordycepin; gallinamide A; plitidepsin; telocinobufagin; tylophorine; SARS-COV-2; MARINE; POTENT; DRUG; CORDYCEPIN; INHIBITOR; STEROIDS;
D O I：
10.3389/fphar.2022.926507
中图分类号：
R9 [药学];
学科分类号：
1007 ;
摘要：
The devastating COVID-19 pandemic has caused more than six million deaths worldwide during the last 2 years. Effective therapeutic agents are greatly needed, yet promising magic bullets still do not exist. Numerous natural products (cordycepin, gallinamide A, plitidepsin, telocinobufagin, and tylophorine) have been widely studied and play a potential function in treating COVID-19. In this paper, we reviewed published studies (from May 2021 to April 2022) relating closely to bioactive natural products (isolated from medicinal plants, animals products, and marine organisms) in COVID-19 therapy in vitro to provide some essential guidance for anti-SARS-CoV-2 drug research and development.
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页数：14
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