SYNTHESIS OF 1,2-DISUBSTITUTED BENZIMIDAZOLES AND 2-SUBSTITUTED BENZOTHIAZOLES CATALYZED BY HCl-TREATED TRANS-3,5-DIHYDROPEROXY-3,5-DIMETHYL-1,2-DIOXOLANE

被引：30
作者：
Azarifar, Davood [1 ]
Khosravi, Kaveh [1 ]
Najminejad, Zohreh [1 ]
Soleimani, Khadijeh [1 ]
机构：
[1] Buali Sina Univ, Dept Chem, Hamadan 65178, Iran
来源：
HETEROCYCLES | 2010年 / 81卷 / 12期
关键词：
ACID-PROMOTED CONDENSATION; SOLVENT-FREE SYNTHESIS; ONE-STEP SYNTHESIS; BIOLOGICAL-PROPERTIES; ANTITUMOR BENZOTHIAZOLES; GREEN SYNTHESIS; IONIC LIQUID; 2-ARYLBENZOTHIAZOLES; ALDEHYDES; AGENTS;
D O I：
10.3987/COM-10-12068
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
The catalytic effect of trans-3,5-dihydroperoxy-3,5-dimethyl-1,2-dioxolane in the presence of HCl has been explored in one-pot condensation reaction of o-phenylenediamines and o-aminobenzenethiol with a variety of aldehydes into their corresponding 2-aryl-1-arylmethylimidazoles and 2-arylbenzothiazoles respectively. The reactions were conducted under mild conditions in MeCN at room temperature to afford the products in excellent yields.
引用
收藏
页码：2855 / 2863
页数：9
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