Biosynthetic studies of versipelostatin, a novel 17-membered α-tetronic acid involved macrocyclic compound isolated from Streptomyces versipellis

被引：19
作者：
Chijiwa, S
Park, HR
Furihata, K
Ogata, M
Endo, T
Kuzuyama, T
Hayakawa, Y
Shin-ya, K [1 ]
机构：
[1] Univ Tokyo, Inst Mol & Cellular Biosci, Bunkyo Ku, Tokyo 1130032, Japan
[2] Univ Tokyo, Grad Sch Agr & Life Sci, Bunkyo Ku, Tokyo 1138657, Japan
[3] Kyoritu Coll Pharm, Minato Ku, Tokyo 1058512, Japan
来源：
TETRAHEDRON LETTERS | 2003年 / 44卷 / 31期
关键词：
versipelostatin; biosynthesis; polyketide; alpha-acyltetronic acid;
D O I：
10.1016/S0040-4039(03)01389-3
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
Versipelostatin, a novel microbial metabolite consisting of a 17-membered macrocyclic aglycone with an alpha-acyltetronic acid functional group and sugar moieties was shown to be biosynthesized through a polyketide intermediate and the involvement of glyceric acid. (C) 2003 Elsevier Ltd. All rights reserved.
引用
收藏
页码：5897 / 5900
页数：4
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