Two New Lignans from Wikstroemia dolichantha

被引：4
作者：
Ma, Qing-Yun [1 ]
Chen, Yong-Lei [1 ,2 ]
Huang, Sheng-Zhuo [1 ]
Kong, Fan-Dong [1 ]
Dai, Hao-Fu [1 ]
Hua, Yan [2 ]
Zhao, You-Xing [1 ]
机构：
[1] CATAS, Hainan Key Lab Res & Dev Nat Prod Li Folk Med, Inst Trop Biosci & Biotechnol, Haikou 571101, Hainan, Peoples R China
[2] Southwest Forestry Univ, Coll Forestry, Kunming 650224, Yunnan, Peoples R China
来源：
CHEMISTRY OF NATURAL COMPOUNDS | 2018年 / 54卷 / 01期
基金：
中国国家自然科学基金;
关键词：
Wikstroemia dolichantha; Thymelaeaceae; lignans; AChE inhibitory activity; INDICA; ROOTS; BIFLAVONOIDS;
D O I：
10.1007/s10600-018-2250-1
中图分类号：
R914 [药物化学];
学科分类号：
100701 ;
摘要：
Two new lignans, dolichanthin A (1) and dolichanthin B (2), were isolated from the EtOAc extract of Wikstroemia dolichantha. Their structures were elucidated by the analysis of 1D and 2D spectroscopic data as well as MS. The inhibitory activity of two isolates against acetylcholinesterase (AChE) revealed that compound 1 exhibited weak inhibitory activity.
引用
收藏
页码：22 / 25
页数：4
相关论文
共 12 条
  • [1] Caffeic Acid Esters and Lignans from Piper sanguineispicum
    Cabanillas, Billy Joel
    Le Lamer, Anne-Cecile
    Castillo, Denis
    Arevalo, Jorge
    Rojas, Rosario
    Odonne, Guillaume
    Bourdy, Genevieve
    Moukarzel, Beatrice
    Sauvain, Michel
    Fabre, Nicolas
    [J]. JOURNAL OF NATURAL PRODUCTS, 2010, 73 (11): : 1884 - 1890
  • [2] A NEW AND RAPID COLORIMETRIC DETERMINATION OF ACETYLCHOLINESTERASE ACTIVITY
    ELLMAN, GL
    COURTNEY, KD
    ANDRES, V
    FEATHERSTONE, RM
    [J]. BIOCHEMICAL PHARMACOLOGY, 1961, 7 (02) : 88 - &
  • [3] FANG JM, 1992, PHYTOCHEMISTRY, V31, P3659, DOI 10.1016/0031-9422(92)83753-L
  • [4] Antifungal, antimitotic and anti-HIV-1 agents from the roots of Wikstroemia indica
    Hu, K
    Kobayashi, H
    Dong, A
    Iwasaki, S
    Yao, XS
    [J]. PLANTA MEDICA, 2000, 66 (06) : 564 - 567
  • [5] A new biflavonoid with antiviral activity from the roots of Wikstroemia indica
    Huang, Wei-Huan
    Zhou, Guang-Xiong
    Wang, Guo-Cai
    Chung, Hau-Yin
    Ye, Wen-Cai
    Li, Yao-Lan
    [J]. JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH, 2012, 14 (04) : 401 - 406
  • [6] Bioactive Components and Pharmacological Action of Wikstroemia indica (L.) C. A. Mey and Its Clinical Application
    Li, Yan-Min
    Zhu, Liang
    Jiang, Jian-Guo
    Yang, Li
    Wang, Ding-Yong
    [J]. CURRENT PHARMACEUTICAL BIOTECHNOLOGY, 2009, 10 (08) : 743 - 752
  • [7] In vitro antimalarial activity of biflavonoids from Wikstroemia indica
    Nunome, S
    Ishiyama, A
    Kobayashi, M
    Otoguro, K
    Kiyohara, H
    Yamada, H
    Omura, S
    [J]. PLANTA MEDICA, 2004, 70 (01) : 76 - 78
  • [8] Toshihiko H., 1994, LIFE SCI, V55, P1061
  • [9] Four New Dilignans from the Roots of Wikstroemia indica
    Wang, Guo-Cai
    Zhang, Xiao-Li
    Wang, Yi-Fei
    Li, Guo-Qiang
    Ye, Wen-Cai
    Li, Yao-Lan
    [J]. CHEMICAL & PHARMACEUTICAL BULLETIN, 2012, 60 (07) : 920 - 923
  • [10] Lignans from the roots of Wikstroemia indica and their DPPH radical scavenging and nitric oxide inhibitory activities
    Wang, LY
    Unehara, N
    Kitanaka, S
    [J]. CHEMICAL & PHARMACEUTICAL BULLETIN, 2005, 53 (10) : 1348 - 1351
12