Synthesis of enantiopure triazolium salts from pyroglutamic acid and their evaluation in the benzoin condensation

被引：110

作者：

Enders, Dieter ^{[1
]}

Han, Jianwei ^{[1
]}

机构：

[1] Univ Aachen, Rhein Westfal TH Aachen, Inst Organ Chem, D-52074 Aachen, Germany

来源：

TETRAHEDRON-ASYMMETRY | 2008年 / 19卷 / 11期

关键词：

D O I：

10.1016/j.tetasy.2008.05.017

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

A family of enantiopure 1,2,4-triazolium salts were prepared starting from the inexpensive (S)-pyroglutamic acid. After treatment with base, the corresponding N-heterocyclic carbenes were tested as organo-catalysts in the asymmetric benzoin condensation and gave good yields and up to 95% ee. (C) 2008 Elsevier Ltd. All rights reserved.

引用

页码：1367 / 1371

页数：5

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