Emotion recognition in Huntington's disease and frontotemporal dementia

被引:111
作者
Snowden, J. S. [1 ]
Austin, N. A. [2 ]
Sembi, S. [3 ]
Thompson, J. C. [1 ]
Craufurd, D. [4 ]
Neary, D. [1 ]
机构
[1] Univ Manchester, Salford Royal Fdn Trust & Clin Neurosci Res Grp, Greater Manchester Neurosci Ctr, Cerebral Funct Unit, Manchester M13 9PL, Lancs, England
[2] Adelaide & Meath Hosp, Dept Psychol, Dublin, Ireland
[3] Univ Plymouth, Plymouth PL4 8AA, Devon, England
[4] Univ Manchester, Med Genet Res Grp, Manchester M13 9PL, Lancs, England
关键词
affect; disgust; anger; degenerative disease;
D O I
10.1016/j.neuropsychologia.2008.04.018
中图分类号
B84 [心理学]; C [社会科学总论]; Q98 [人类学];
学科分类号
03 ; 0303 ; 030303 ; 04 ; 0402 ;
摘要
A well-documented feature of Huntington's disease (HID) is disproportionate impairment in the ability to recognise the emotional expression of disgust. However, this finding has been challenged by studies that report no differential disgust impairment and attribute apparent differences across emotions to task difficulty. The present study sought to shed light on disparities in findings through a comparative study of emotion recognition in HD and frontotemporal dementia (FTD). Ten HD, 12 FTD patients and 12 healthy controls were administered 10 tasks assessing facial and vocal recognition of emotions and comprehension of emotion terms. The findings were not consistent with either the 'selective disgust impairment' or 'task difficulty' view. Both HID and FTD groups were impaired compared to controls, deficits in HID being less severe. Impairments in FTD were elicited for all emotions whereas in HD they were demonstrated predominantly for negative emotions of fear, disgust and anger. Consistency in performance, despite varying task demands, excluded an explanation in terms of item difficulty, and was in keeping with the notion of distinct neural substrates for processing of negative emotions. Contrary to the notion of disproportionate disgust impairment, the most severe deficits in HD were elicited for anger, a finding that may have relevance for the poor anger control that is the hallmark of HD. The data raise the possibility that linguistic influences and conceptual complexities of the emotion of disgust may contribute to the variable finding of selective disgust impairment in HD. (C) 2008 Elsevier Ltd. All rights reserved.
引用
收藏
页码:2638 / 2649
页数:12
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