Failure of cefepime therapy in treatment of Klebsiella pneumoniae bacteremia

被引：39
作者：
Song, W
Moland, ES
Hanson, ND
Lewis, JS
Jorgensen, JH
Thomson, KS
机构：
[1] Creighton Univ, Sch Med, Dept Med Microbiol & Immunol, Ctr Res Antiinfect & Biotechnol, Omaha, NE 68178 USA
[2] Univ Texas, Hlth Sci Ctr, Dept Pharmacol, San Antonio, TX 78229 USA
[3] Univ Texas, Hlth Sci Ctr, Dept Pathol, San Antonio, TX 78229 USA
来源：
JOURNAL OF CLINICAL MICROBIOLOGY | 2005年 / 43卷 / 09期
关键词：
D O I：
10.1128/JCM.43.9.4891-4894.2005
中图分类号：
Q93 [微生物学];
学科分类号：
071005 ; 100705 ;
摘要：
A case of failure of cefepime treatment of a bloodstream infection with AmpC-producing Klebsiella pneumoniae is reported. The failure was attributed to extended-spectrum beta-lactamase (ESBL) acquisition by the isolate, possibly during therapy. Problems encountered with ESBL detection in AmpC-producing isolates are discussed.
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收藏
页码：4891 / 4894
页数：4
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