Synthetic studies toward gambierol. Convergent synthesis of the octacyclic polyether core

被引：39

作者：

Fuwa, H

Sasaki, M

Tachibana, K

机构：

[1] Univ Tokyo, Grad Sch Sci, Dept Chem, Bunkyo Ku, Tokyo 1130033, Japan

[2] Japan Sci & Technol Corp, JST, CREST, Bunkyo Ku, Tokyo 1130033, Japan

[3] Tohoku Univ, Grad Sch Life Sci, Dept Biomol Sci, Sendai, Miyagi 9818555, Japan

来源：

ORGANIC LETTERS | 2001年 / 3卷 / 22期

关键词：

D O I：

10.1021/ol0166597

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

[GRAPHICS] A convergent synthetic route to the octacyclic polyether core of gambierol, a marine polycyclic ether toxin, has been developed, The synthesis involves construction of two fragments representing the ABC and EFGH ring systems followed by their coupling via a B-alkyl Suzuki reaction.

引用

页码：3549 / 3552

页数：4