Multiplexed DNA Detection with DNA-Functionalized Silver and Silver/Gold Nanoparticle Superstructure Probes

被引：12

作者：

Kim, Ji-Young ^{[1
]}

Lee, Jae-Seung ^{[1
]}

机构：

[1] Korea Univ, Dept Mat Sci & Engn, Seoul 136713, South Korea

来源：

BULLETIN OF THE KOREAN CHEMICAL SOCIETY | 2012年 / 33卷 / 01期

基金：

新加坡国家研究基金会;

关键词：

DNA; SPR; Nanoparticle superstructure; Multiplexing; Colorimetric detection; ENHANCED RAMAN-SCATTERING; SPECTROSCOPY; FABRICATION; CRYSTALS; ARRAYS;

D O I：

10.5012/bkcs.2012.33.1.221

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

DNA-functionalized silver and silver/gold bimetallic nanoparticle superstructure probes with controllable sizes and optical properties are synthesized using monothiol DNA and dithiothreitol. The superstructures exhibit a very narrow size distribution, which can be easily controlled by balancing the ratio of dithiothreitol and DNA. These superstructures assemble reversibly in a highly cooperative manner, and are SERS active. Multiplexed colorimetric detection of DNA targets using these superstructure probes has been demonstrated to identify three different DNA target sequences that are associated with three lethal diseases, respectively.

引用

页码：221 / 226

页数：6

共 35 条

[21] Fabrication and Use of Electroless Plated Polymer Surface-Enhanced Raman Spectroscopy Substrates for Viral Gene Detection [J].

Malvadkar, Niranjan A. ;

Demirel, Gokhan ;

Poss, Mary ;

Javed, Ali ;

Dressick, Walter J. ;

Demirel, Melik C. .

JOURNAL OF PHYSICAL CHEMISTRY C, 2010, 114 (24) :10730-10738

[22] RETRACTED: A DNA-based method for rationally assembling nanoparticles into macroscopic materials (Retracted article. See vol. 671, 2023) [J].

Mirkin, CA ;

Letsinger, RL ;

Mucic, RC ;

Storhoff, JJ .

NATURE, 1996, 382 (6592) :607-609

[23] Submicrometer metallic barcodes [J].

Nicewarner-Peña, SR ;

Freeman, RG ;

Reiss, BD ;

He, L ;

Peña, DJ ;

Walton, ID ;

Cromer, R ;

Keating, CD ;

Natan, MJ .

SCIENCE, 2001, 294 (5540) :137-141

[24]

Niemeyer CM, 1999, ANGEW CHEM INT EDIT, V38, P2865, DOI 10.1002/(SICI)1521-3773(19991004)38:19<2865::AID-ANIE2865>3.0.CO

[25]

2-F

[26] DNA-based assembly of metal nanoparticles [J].

Niemeyer, CM ;

Simon, U .

EUROPEAN JOURNAL OF INORGANIC CHEMISTRY, 2005, (18) :3641-3655

[27] Structures of DNA-linked nanoparticle aggregates [J].

Park, Sung Yong ;

Lee, Jae-Seung ;

Georganopoulou, Dimitra ;

Mirkin, Chad A. ;

Schatz, George C. .

JOURNAL OF PHYSICAL CHEMISTRY B, 2006, 110 (25) :12673-12681

[28] Mixed silver/gold colloids: A study of their formation, morphology, and surface-enhanced Raman activity [J].

Rivas, L ;

Sanchez-Cortes, S ;

Garcia-Ramos, JV ;

Morcillo, G .

LANGMUIR, 2000, 16 (25) :9722-9728

[29] Multiplexed DNA detection with biobarcoded nanoparticle probes [J].

Stoeva, Savka I. ;

Lee, Jae-Seung ;

Thaxton, C. Shad ;

Mirkin, Chad A. .

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2006, 45 (20) :3303-3306

[30] Controllable Synthesis of Silver Nanoparticle Aggregates for Surface-Enhanced Raman Scattering Studies [J].

Sun, Lanlan ;

Zhao, Dongxu ;

Ding, Meng ;

Xu, ZhiKun ;

Zhang, Zhenzhong ;

Li, Binghui ;

Shen, Dezhen .

JOURNAL OF PHYSICAL CHEMISTRY C, 2011, 115 (33) :16295-16304

← 1 2 3 4 →