Psychollatine, a glucosidic monoterpene indole alkaloid from Psychotria umbellata

被引：41
作者：
Kerber, V. A. [1 ]
Passos, C. S. [1 ]
Verli, H. [1 ,2 ]
Fett-Neto, A. G.
Quirion, J. P. [3 ]
Henriques, A. T. [1 ]
机构：
[1] Univ Fed Rio Grande do Sul, Programa Posgrad Ciencias Farm, Fac Farm, BR-90610000 Porto Alegre, RS, Brazil
[2] Univ Fed Rio Grande do Sul, Ctr Biotechnol, BR-91500970 Porto Alegre, RS, Brazil
[3] Inst Natl Sci Appl Rouen, Intitut Rocherche & Chim Organ fine, Lab Heterochim Organ, F-76131 Mt St Again, France
来源：
JOURNAL OF NATURAL PRODUCTS | 2008年 / 71卷 / 04期
关键词：
D O I：
10.1021/np0703951
中图分类号：
Q94 [植物学];
学科分类号：
071001 ;
摘要：
A monoterpene indole alkaloid, psychollatine (1), was isolated from Psychotria umbellata leaves. Its structure was characterized by interpretation of spectroscopic data and by comparison of its NMR data with those of croceaine A (2) from Palicourea crocea. The configuration of psychollatine (1) was established by NOE difference and circular dichroism (CD) techniques, while its conformation was evaluated through molecular modeling studies and NMR coupling constants.
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页码：697 / 700
页数：4
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