Influence of magnetoplasmonic γ-Fe2O3/Au core/shell nanoparticles on low-field nuclear magnetic resonance

被引：16

作者：

Chen, Kuen-Lin ^{[1
]}

Yeh, Yao-Wei ^{[1
]}

Chen, Jian-Ming ^{[2
]}

Hong, Yu-Jie ^{[1
]}

Huang, Tsung-Lin ^{[1
]}

Deng, Zu-Yin ^{[1
]}

Wu, Chiu-Hsien ^{[1
,2
]}

Liao, Su-Hsien ^{[3
]}

Wang, Li-Min ^{[4
,5
]}

机构：

[1] Natl Chung Hsing Univ, Dept Phys, Taichung 402, Taiwan

[2] Natl Chung Hsing Univ, Inst Nanosci, Taichung 402, Taiwan

[3] Natl Taiwan Normal Univ, Inst Electroopt Sci & Technol, Taipei 116, Taiwan

[4] Natl Taiwan Univ, Grad Inst Appl Phys, Taipei 106, Taiwan

[5] Natl Taiwan Univ, Dept Phys, Taipei 106, Taiwan

来源：

SCIENTIFIC REPORTS | 2016年 / 6卷

关键词：

IRON-OXIDE NANOPARTICLES; CONTRAST AGENTS; MRI; HYPERTHERMIA; ENHANCEMENT;

D O I：

10.1038/srep35477

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

Magnetoplasmonic nanoparticles, composed of a plasmonic layer and a magnetic core, have been widely shown as promising contrast agents for magnetic resonance imaging (MRI) applications. However, their application in low-field nuclear magnetic resonance (LFNMR) research remains scarce. Here we synthesised gamma-Fe2O3/Au core/shell (gamma-Fe2O3@Au) nanoparticles and subsequently used them in a homemade, high-Tc, superconducting quantum interference device (SQUID) LFNMR system. Remarkably, we found that both the proton spin-lattice relaxation time (T-1) and proton spin-spin relaxation time (T-2) were influenced by the presence of gamma-Fe2O3@Au nanoparticles. Unlike the spin-spin relaxation rate (1/T-2), the spin-lattice relaxation rate (1/T-1) was found to be further enhanced upon exposing the gamma-Fe2O3@Au nanoparticles to 532 nm light during NMR measurements. We showed that the photothermal effect of the plasmonic gold layer after absorbing light energy was responsible for the observed change in T-1. This result reveals a promising method to actively control the contrast of T-1 and T-2 in low-field (LF) MRI applications.

引用

页数：8

共 27 条

[11] Characterizing the field-dependent T1-relaxation and imaging of ferrofluids using high-Tc superconducting quantum interference device magnetometer in low magnetic fields [J].