Nonmelanoma Skin Cancer in Inflammatory Bowel Disease: A Review

被引:49
|
作者
Long, Millie D. [1 ]
Kappelman, Michael D. [2 ]
Pipkin, Clare A. [3 ]
机构
[1] Univ N Carolina, Dept Med, Div Gastroenterol & Hepatol, Chapel Hill, NC 27599 USA
[2] Univ N Carolina, Dept Pediat, Div Gastroenterol & Hepatol, Chapel Hill, NC 27599 USA
[3] Duke Univ, Dept Dermatol, Durham, NC USA
基金
美国国家卫生研究院;
关键词
nonmelanoma skin cancer; immunosuppression; anti-TNF agents; inflammatory bowel disease; prevention; TUMOR-NECROSIS-FACTOR; RHEUMATOID-ARTHRITIS; CELL CARCINOMA; RISK; AZATHIOPRINE; MALIGNANCIES; THERAPY;
D O I
10.1002/ibd.21484
中图分类号
R57 [消化系及腹部疾病];
学科分类号
摘要
At least 1 million new cases of nonmelanoma skin cancer (NMSC) are diagnosed in the United States each year and the incidence is increasing. A higher incidence of NMSC in organ transplant recipients on immunosuppression has been documented for some time, and recent studies indicate that patients with inflammatory bowel disease (IBD), particularly those treated with immunosuppressive medications, might also be at higher risk for this condition. In this review we summarize recent data evaluating the associations between immunomodulators, antitumor necrosis factor-a biologic agents and NMSC in patients with IBD and other autoimmune conditions such as rheumatoid arthritis. We also offer recommendations for prevention of NMSC in these populations.
引用
收藏
页码:1423 / 1427
页数:5
相关论文
共 50 条
  • [1] Thiopurines and Risk of Nonmelanoma Skin Cancer in Inflammatory Bowel Disease
    Ramiscal, Judi Anne B.
    Brewer, Jerry D.
    JAMA DERMATOLOGY, 2013, 149 (01) : 92 - 94
  • [2] Risk of Melanoma and Nonmelanoma Skin Cancer Among Patients With Inflammatory Bowel Disease
    Long, Millie D.
    Martin, Christopher F.
    Pipkin, Clare A.
    Herfarth, Hans H.
    Sandler, Robert S.
    Kappelman, Michael D.
    GASTROENTEROLOGY, 2012, 143 (02) : 390 - +
  • [3] Nonmelanoma Skin Cancer Risk in Patients With Inflammatory Bowel Disease Undergoing Thiopurine Therapy: A Systematic Review of the Literature
    Hagen, Joshua W.
    Pugliano-Mauro, Melissa A.
    DERMATOLOGIC SURGERY, 2018, 44 (04) : 469 - 480
  • [4] Risk of Nonmelanoma Skin Cancer in Patients With Inflammatory Bowel Disease Who Use Thiopurines Is Not Increased
    van Schaik, Fiona D. M.
    van Oijen, Martijn G. H.
    Smeets, Hugo M.
    van der Heijden, Geert J. M. G.
    Siersema, Peter D.
    Oldenburg, Bas
    CLINICAL GASTROENTEROLOGY AND HEPATOLOGY, 2011, 9 (05) : 449 - 450
  • [5] Increased Risk of Nonmelanoma Skin Cancers Among Individuals With Inflammatory Bowel Disease
    Singh, Harminder
    Nugent, Zoann
    Demers, Alain A.
    Bernstein, Charles N.
    GASTROENTEROLOGY, 2011, 141 (05) : 1612 - 1620
  • [6] Risk of nonmelanoma skin cancer in patients taking Janus kinase inhibitors for inflammatory bowel disease: A systematic review and meta-analysis
    Liu, Chuen-Huei
    Hou, Wen-Hsuan
    Lin, Pi-Chu
    Kang, Yi-No
    Liu, Wei-Ting
    Chen, Su-Ru
    DERMATOLOGICA SINICA, 2024, 42 (03)
  • [7] Nonmelanoma Skin Cancers in Inflammatory Bowel Disease Patients Treated With Thiopurines: A Systematic Review and Meta-Analysis
    Thosani, Nirav
    Mehta, Shivang
    Wolf, David S.
    Dupont, Andrew W.
    Fallon, Michael B.
    Guha, Sushovan
    GASTROENTEROLOGY, 2012, 142 (05) : S401 - S402
  • [8] Physicians May Inadequately Counsel Inflammatory Bowel Disease Patients About Immunosuppressive Therapy and Risk of Nonmelanoma Skin Cancer
    Borum, Marie L.
    Sidhu, Harjiwander Preethi
    Bornstein, Leigh
    INFLAMMATORY BOWEL DISEASES, 2011, 17 (05) : 1246 - 1246
  • [9] Increased Risk for Nonmelanoma Skin Cancers in Patients Who Receive Thiopurines for Inflammatory Bowel Disease
    Peyrin-Biroulet, Laurent
    Khosrotehrani, Kiarash
    Carrat, Fabrice
    Bouvier, Anne-Marie
    Chevaux, Jean-Baptiste
    Simon, Tabassome
    Carbonnel, Frank
    Colombel, Jean-Frederic
    Dupas, Jean-Louis
    Godeberge, Philippe
    Hugot, Jean-Pierre
    Lemann, Marc
    Nahon, Stephane
    Sabate, Jean-Marc
    Tucat, Gilbert
    Beaugerie, Laurent
    GASTROENTEROLOGY, 2011, 141 (05) : 1621 - U150
  • [10] Physicians inadequately counsel Inflammatory Bowel Disease patients about Immunosuppressive Therapy and the risk of nonmelanoma skin cancer with sun exposure
    Sidhu, H.
    Bornstein, L.
    Chandler, M.
    Borum, M.
    INFLAMMATORY BOWEL DISEASES, 2008, 14 (12) : S4 - S4