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The Complexity of the Gapped Consecutive-Ones Property Problem for Matrices of Bounded Maximum Degree
被引:0
|作者:
Manuch, Jan
[1
,2
]
Patterson, Murray
[2
]
机构:
[1] Simon Fraser Univ, Dept Math, Burnaby, BC V5A 1S6, Canada
[2] Univ British Columbia, Dept Comp Sci, Vancouver, BC, Canada
来源:
COMPARATIVE GENOMICS
|
2010年
/
6398卷
基金:
加拿大自然科学与工程研究理事会;
关键词:
GALLED-TREE NETWORKS;
D O I:
暂无
中图分类号:
Q5 [生物化学];
学科分类号:
071010 ;
081704 ;
摘要:
The Gapped Consecutive-Ones Property (C1P) Problem, or the (k, delta)-C1P Problem is: given a binary matrix M and integers k and 5, decide if the columns of M can be ordered such that each row contains at most k blocks of and no two neighboring blocks of are separated by a gap of more than delta 0's. This problem was introduced in [3]. The classical polynomial-time solvable C1P Problem is equivalent to the (1, 0)-C1P problem. It has been shown that for every unbounded or bounded k >= 2 and unbounded or bounded delta >= 1, except when (k, delta) = (2,1), the (k, delta)-C1P Problem is NP-complete [10,6]. In this paper we study the Gapped C1P Problem with a third parameter d, namely the bound on the maximum number of l's in any row of M or the bound on the maximum degree of M. This is motivated by problems in comparative genomics and paleogenomics, where the genome data is often sparse [4]. The (d, k, delta)-C1P Problem has been shown to be polynomial-time solvable when all three parameters are fixed [3]. Since fixing d also fixes k (k <= d), the only case left to consider is the case when (5 is unbounded, or the (d, k, infinity)-C1P Problem. Here we show that for every d > k >= 2, the (d, k, infinity)-C1P Problem is NP-complete.
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页码:278 / +
页数:2
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