Synchronization and rhythmic processes in physiology

被引:1016
作者
Glass, L [1 ]
机构
[1] McGill Univ, Dept Physiol, Ctr Nonlinear Dynam Physiol & Med, Montreal, PQ H3G 1Y6, Canada
关键词
D O I
10.1038/35065745
中图分类号
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号
07 ; 0710 ; 09 ;
摘要
Complex bodily rhythms are ubiquitous in living organisms. These rhythms arise from stochastic, nonlinear biological mechanisms interacting with a fluctuating environment. Disease often leads to alterations from normal to pathological rhythm. Fundamental questions concerning the dynamics of these rhythmic processes abound. For example, what is the origin of physiological rhythms? How do the rhythms interact with each other and the external environment? Can we decode the fluctuations in physiological rhythms to better diagnose human disease? And can we develop better methods to control pathological rhythms? Mathematical and physical techniques combined with physiological and medical studies are addressing these questions and are transforming our understanding of the rhythms of life.
引用
收藏
页码:277 / 284
页数:8
相关论文
共 93 条
[1]   Modeling circadian rhythm generation in the suprachiasmatic nucleus with locally coupled self-sustained oscillators: Phase shifts and phase response curves [J].
Achermann, P ;
Kunz, H .
JOURNAL OF BIOLOGICAL RHYTHMS, 1999, 14 (06) :460-468
[2]   LOW-DIMENSIONAL CHAOS IN AN INSTANCE OF EPILEPSY [J].
BABLOYANTZ, A ;
DESTEXHE, A .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1986, 83 (10) :3513-3517
[3]  
Bak P. P., 1996, NATURE WORKS
[4]  
Bassingthwaighte J. B., 1994, FRACTAL PHYSL, DOI DOI 10.1007/978-1-4614-7572-9
[5]   Tremor in Cree subjects exposed to methylmercury: A preliminary study [J].
Beuter, A ;
Edwards, R .
NEUROTOXICOLOGY AND TERATOLOGY, 1998, 20 (06) :581-589
[6]   Models of respiratory rhythm generation in the pre-Botzinger complex. II. Populations of coupled pacemaker neurons [J].
Butera, RJ ;
Rinzel, J ;
Smith, JC .
JOURNAL OF NEUROPHYSIOLOGY, 1999, 82 (01) :398-415
[7]  
Camm AJ, 1996, CIRCULATION, V93, P1043
[8]  
Christini DJ, 2001, HDB BIOL PHYS, V4, P205
[9]   Noise-enhanced information transmission in rat SA1 cutaneous mechanoreceptors via aperiodic stochastic resonance [J].
Collins, JJ ;
Imhoff, TT ;
Grigg, P .
JOURNAL OF NEUROPHYSIOLOGY, 1996, 76 (01) :642-645
[10]   Noise-mediated enhancements and decrements in human tactile sensation [J].
Collins, JJ ;
Imhoff, TT ;
Grigg, P .
PHYSICAL REVIEW E, 1997, 56 (01) :923-926