NOTCH mutations as prognostic markers in T-ALL

被引：24

作者：

Ferrando, A. ^{[1
,2
,3
]}

机构：

[1] Columbia Univ, Med Ctr, Inst Canc Genet, New York, NY 10027 USA

[2] Columbia Univ, Med Ctr, Dept Pediat, New York, NY USA

[3] Columbia Univ, Med Ctr, Dept Pathol, New York, NY USA

来源：

LEUKEMIA | 2010年 / 24卷 / 12期

关键词：

RESISTANCE; ACTIVATION;

D O I：

10.1038/leu.2010.237

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

引用

页码：2003 / 2004

页数：2

共 14 条

[1] NOTCH1/FBXW7 mutation identifies a large subgroup with favorable outcome in adult T-cell acute lymphoblastic leukemia (T-ALL): a Group for Research on Adult Acute Lymphoblastic Leukemia (GRAALL) study [J].

Asnafi, Vahid ;

Buzyn, Agnes ;

Le Noir, Sandrine ;

Baleydier, Frederic ;

Simon, Arnauld ;

Beldjord, Kheira ;

Reman, Oumedaly ;

Witz, Francis ;

Fagot, Thierry ;

Tavernier, Emmanuelle ;

Turlure, Pascal ;

Leguay, Thibaut ;

Huguet, Francoise ;

Vernant, Jean-Paul ;

Daniel, Francis ;

Bene, Marie-Christine ;

Ifrah, Norbert ;

Thomas, Xavier ;

Dombret, Herve ;

Macintyre, Elizabeth .

BLOOD, 2009, 113 (17) :3918-3924

[2] Activating NOTCH1 mutations predict favorable early treatment response and long-term outcome in childhood precursor T-cell lymphoblastic leukemia [J].

Breit, Stephen ;

Stanulla, Martin ;

Flohr, Thomas ;

Schrappe, Martin ;

Ludwig, Wolf-Dieter ;

Tolle, Gabriele ;

Happich, Margit ;

Muckenthaler, Martina U. ;

Kulozik, Andreas E. .

BLOOD, 2006, 108 (04) :1151-1157

[3] Correlating notch signaling with thymocyte maturation [J].

Deftos, ML ;

He, YW ;

Ojala, EW ;

Bevan, MJ .

IMMUNITY, 1998, 9 (06) :777-786

[4] Absence of Biallelic TCRγ Deletion Predicts Early Treatment Failure in Pediatric T-Cell Acute Lymphoblastic Leukemia [J].

Gutierrez, Alejandro ;

Dahlberg, Suzanne E. ;

Neuberg, Donna S. ;

Zhang, Jianhua ;

Grebliunaite, Ruta ;

Sanda, Takaomi ;

Protopopov, Alexei ;

Tosello, Valeria ;

Kutok, Jeffery ;

Larson, Richard S. ;

Borowitz, Michael J. ;

Loh, Mignon L. ;

Ferrando, Adolfo A. ;

Winter, Stuart S. ;

Mullighan, Charles G. ;

Silverman, Lewis B. ;

Chin, Lynda ;

Hunger, Stephen P. ;

Sallan, Stephen E. ;

Look, A. Thomas .

JOURNAL OF CLINICAL ONCOLOGY, 2010, 28 (24) :3816-3823

[5] Prognostic Implications of NOTCH1 and FBXW7 Mutations in Adults With T-Cell Acute Lymphoblastic Leukemia Treated on the MRC UKALLXII/ECOG E2993 Protocol [J].

Mansour, Marc R. ;

Sulis, Maria L. ;

Duke, Veronique ;

Foroni, Letizia ;

Jenkinson, Sarah ;

Koo, Kenneth ;

Allen, Christopher G. ;

Gale, Rosemary E. ;

Buck, Georgina ;

Richards, Sue ;

Paietta, Elisabeth ;

Rowe, Jacob M. ;

Tallman, Martin S. ;

Goldstone, Anthony H. ;

Ferrando, Adolfo A. ;

Linch, David C. .

JOURNAL OF CLINICAL ONCOLOGY, 2009, 27 (26) :4352-4356

[6] FBW7 mutations in leukemic cells mediate NOTCH pathway activation and resistance to γ-secretase inhibitors [J].

O'Neil, Jennifer ;

Grim, Jonathan ;

Strack, Peter ;

Rao, Sudhir ;

Tibbitts, Deanne ;

Winter, Christopher ;

Hardwick, James ;

Welcker, Markus ;

Meijerink, Jules P. ;

Pieters, Rob ;

Draetta, Giulio ;

Sears, Rosalie ;

Clurman, Bruce E. ;

Look, A. Thomas .

JOURNAL OF EXPERIMENTAL MEDICINE, 2007, 204 (08) :1813-1824

[7] CUTLL1, a novel human T-cell lymphoma cell line with t(7;9) rearrangement, aberrant NOTCH1 activation and high sensitivity to γ-secretase inhibitors [J].

Palomero, T. ;

Barnes, K. C. ;

Real, P. J. ;

Bender, J. L. Glade ;

Sulis, M. L. ;

Murty, V. V. ;

Colovai, A. I. ;

Balbin, M. ;

Ferrando, A. A. .

LEUKEMIA, 2006, 20 (07) :1279-1287

[8] NOTCH inhibition and glucocorticoid therapy in T-cell acute lymphoblastic leukemia [J].

Real, P. J. ;

Ferrando, A. A. .

LEUKEMIA, 2009, 23 (08) :1374-1377

[9] γ-secretase inhibitors reverse glucocorticoid resistance in T cell acute lymphoblastic leukemia [J].

Real, Pedro J. ;

Tosello, Valeria ;

Palomero, Teresa ;

Castillo, Mireia ;

Hernando, Eva ;

de Stanchina, Elisa ;

Sulis, Maria Luisa ;

Barnes, Kelly ;

Sawai, Catherine ;

Homminga, Irene ;

Meijerink, Jules ;

Aifantis, Iannis ;

Basso, Giuseppe ;

Cordon-Cardo, Carlos ;

Ai, Walden ;

Ferrando, Adolfo .

NATURE MEDICINE, 2009, 15 (01) :50-58

[10] Improved Early Event-Free Survival With Imatinib in Philadelphia Chromosome-Positive Acute Lymphoblastic Leukemia: A Children's Oncology Group Study [J].

Schultz, Kirk R. ;

Bowman, W. Paul ;

Aledo, Alexander ;

Slayton, William B. ;

Sather, Harland ;

Devidas, Meenakshi ;

Wang, Chenguang ;

Davies, Stella M. ;

Gaynon, Paul S. ;

Trigg, Michael ;

Rutledge, Robert ;

Burden, Laura ;

Jorstad, Dean ;

Carroll, Andrew ;

Heerema, Nyla A. ;

Winick, Naomi ;

Borowitz, Michael J. ;

Hunger, Stephen P. ;

Carroll, William L. ;

Camitta, Bruce .

JOURNAL OF CLINICAL ONCOLOGY, 2009, 27 (31) :5175-5181

← 1 2 →