Highly Sensitive and Selective Sensing of Free Bilirubin Using Metal-Organic Frameworks-Based Energy Transfer Process

被引：190
作者：
Du, Yaran [1 ]
Li, Xiqian [2 ]
Lv, Xueju [1 ]
Jia, Qiong [1 ]
机构：
[1] Jilin Univ, Coll Chem, Changchun 130012, Jilin, Peoples R China
[2] Jilin Univ, China Japan Hosp, Changchun 130033, Jilin, Peoples R China
来源：
ACS APPLIED MATERIALS & INTERFACES | 2017年 / 9卷 / 36期
关键词：
free bilirubin; fluorescent sensor; postsynthetic modification; metal-organic frameworks; fluorescent resonant energy transfer; STABILIZED GOLD NANOCLUSTERS; COORDINATION POLYMERS; FLUORESCENCE; LUMINESCENT; PHOSPHORESCENCE; PROBE; MOF; NANOPARTICLES; CONSTRUCTION; EPOXIDATION;
D O I：
10.1021/acsami.7b09091
中图分类号：
TB3 [工程材料学];
学科分类号：
0805 ; 080502 ;
摘要：
Free bilirubin, a key biomarker for jaundice, was detected with a newly designed fluorescent postsynthetically modified metal organic framework (MOP) (UIO-66-PSM) sensor. UiO-66-PSM was prepared based on the aldimine condensation reaction of UiO-66-NH2 with 2,3,4-trihydroxybenzaldehyde. The fluorescence of UIO-66-PSM could be effectively quenched by free bilirubin via a fluorescent resonant energy transfer process, thus achieving its recognition of free bilirubin. It was the first attempt to design a MOF-based fluorescent probe for sensing free bilirubin. The probe exhibited fast response time, low detection limit, wide linear range, and high selectivity toward free bilirubin. The sensing system enabled the monitor of free bilirubin in real human serum. Hence, the reported free bilirubin sensing platform has potential applications for clinical diagnosis of jaundice.
引用
收藏
页码：30925 / 30932
页数：8
相关论文
共 57 条
[1]   Construction of an amperometric bilirubin biosensor based on covalent immobilization of bilirubin oxidase onto zirconia coated silica nanoparticles/chitosan hybrid film [J].
Batra, Bhawna ;
Lata, Suman ;
Sunny ;
Rana, J. S. ;
Pundir, Chandra Shekhar .
BIOSENSORS & BIOELECTRONICS, 2013, 44 :64-69
[2]   Ultrafast deactivation of bilirubin: dark intermediates and two-photon isomerization [J].
Carreira-Blanco, Carlos ;
Singer, Patrick ;
Diller, Rolf ;
Perez Lustres, J. Luis .
PHYSICAL CHEMISTRY CHEMICAL PHYSICS, 2016, 18 (10) :7148-7155
[3]   A ratiometric fluorescent nanoprobe based on terbium functionalized carbon dots for highly sensitive detection of an anthrax biomarker [J].
Chen, Hao ;
Xie, Yujie ;
Kirillov, Alexander M. ;
Liu, Liangliang ;
Yu, Minghui ;
Liu, Weisheng ;
Tang, Yu .
CHEMICAL COMMUNICATIONS, 2015, 51 (24) :5036-5039
[4]   Via zinc(II) protoporphyrin to the synthesis of poly(ZnPP-MAA-EGDMA) for the imprinting and selective binding of bilirubin [J].
Chou, Shih-Kai ;
Syu, Mei-Jywan .
BIOMATERIALS, 2009, 30 (07) :1255-1262
[5]   Postsynthetic Methods for the Functionalization of Metal-Organic Frameworks [J].
Cohen, Seth M. .
CHEMICAL REVIEWS, 2012, 112 (02) :970-1000
[6]   Metal-Organic Frameworks as Platforms for Functional Materials [J].
Cui, Yuanjing ;
Li, Bin ;
He, Huajun ;
Zhou, Wei ;
Chen, Banglin ;
Qian, Guodong .
ACCOUNTS OF CHEMICAL RESEARCH, 2016, 49 (03) :483-493
[7]   A Luminescent Mixed-Lanthanide Metal-Organic Framework Thermometer [J].
Cui, Yuanjing ;
Xu, Hui ;
Yue, Yanfeng ;
Guo, Zhiyong ;
Yu, Jiancan ;
Chen, Zhenxia ;
Gao, Junkuo ;
Yang, Yu ;
Qian, Guodong ;
Chen, Banglin .
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2012, 134 (09) :3979-3982
[8]   Luminescent Functional Metal-Organic Frameworks [J].
Cui, Yuanjing ;
Yue, Yanfeng ;
Qian, Guodong ;
Chen, Banglin .
CHEMICAL REVIEWS, 2012, 112 (02) :1126-1162
[9]   Highly Selective Detection of Trinitrophenol by Luminescent Functionalized Reduced Graphene Oxide through FRET Mechanism [J].
Dinda, Diptiman ;
Gupta, Abhisek ;
Shaw, Bikash Kumar ;
Sadhu, Suparna ;
Saha, Shyamal Kumar .
ACS APPLIED MATERIALS & INTERFACES, 2014, 6 (13) :10722-10728
[10]   Establishment of highly sensitive and selective fluorescent sensor for Fe3+ based on a post-synthetic modification of metal-organic framework [J].
Du, Yaran ;
Song, Naizhong ;
Lv, Xueju ;
Hu, Bin ;
Zhou, Weihong ;
Jia, Qiong .
DYES AND PIGMENTS, 2017, 138 :15-22
123456