Shapes of RNA Pseudoknot Structures

被引:11
作者
Reidys, Christian M. [1 ]
Wang, Rita R. [1 ]
机构
[1] Nankai Univ, LPMC TJKLC, Ctr Combinator, Tianjin 300071, Peoples R China
基金
美国国家科学基金会;
关键词
sigma-canonical; generating function; k-noncrossing RNA structure; shape; singularity analysis; SECONDARY STRUCTURE; COMBINATORICS; PREDICTION; MATCHINGS;
D O I
10.1089/cmb.2010.0006
中图分类号
Q5 [生物化学];
学科分类号
071010 ; 081704 ;
摘要
In this article, we study abstract shapes of k-noncrossing, sigma-canonical RNA pseudoknot structures. We consider lv(k)(1)- and lv(k)(5)-shapes, which represent a generalization of the abstract pi- and pi-shapes of RNA secondary structures introduced by Giegerich et al. Using a novel approach, we compute the generating functions of lv(k)(1)- and lv(k)(5)-shapes as well as the generating functions of all lv(k)(1)- and lv(k)(5)-shapes induced by all k-noncrossing, sigma-canonical RNA structures for fixed n. By means of singularity analysis of the generating functions, we derive explicit asymptotic expressions For online Supplementary Material, see www.liebertonline.com.
引用
收藏
页码:1575 / 1590
页数:16
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