Ethical challenges in stroke research

被引：23
作者：
Slyter, H [1 ]
机构：
[1] Kaiser Fdn Hosp, Permanente Med Grp, Sacramento, CA 95825 USA
来源：
STROKE | 1998年 / 29卷 / 08期
关键词：
clinical trials; ethics; medical; informed consent;
D O I：
10.1161/01.STR.29.8.1725
中图分类号：
R74 [神经病学与精神病学];
学科分类号：
摘要：
Background-Ethical issues are a critical consideration in the design and conduct of clinical research. Summary of Review-A number of completed trials of proposed stroke treatments raise classical ethical issues in challenging ways. The combination of acutely ill and vulnerable patients, the use of potentially toxic drugs, and very short time frames for decision making and drug administration demand an especially careful evaluation of risk and benefit, the process of consent, and the permissible treatment of control patients. Conclusions-The study of acute stroke treatments may require more complex safeguards than other neuroclinical trials.
引用
收藏
页码：1725 / 1729
页数：5
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