Metabolic and nutritional support of critically ill patients: consensus and controversies

被引:279
作者
Preiser, Jean-Charles [1 ]
van Zanten, Arthur R. H. [2 ]
Berger, Mette M. [3 ]
Biolo, Gianni [4 ]
Casaer, Michael P. [5 ]
Doig, Gordon S. [6 ]
Griffiths, Richard D. [7 ]
Heyland, Daren K. [8 ]
Hiesmayr, Michael [9 ]
Iapichino, Gaetano [10 ]
Laviano, Alessandro [11 ]
Pichard, Claude [12 ]
Singer, Pierre [13 ]
Van den Berghe, Greet [5 ]
Wernerman, Jan [14 ]
Wischmeyer, Paul [15 ]
Vincent, Jean-Louis [1 ]
机构
[1] Univ Libre Bruxelles, Erasme Univ Hosp, Dept Intens Care, B-1070 Brussels, Belgium
[2] Gelderse Vallei Hosp, Dept Intens Care, NL-6716 RP Ede Gld, Netherlands
[3] CHUV BH, Serv Med Intens Adulte & Brules, CH-1011 Lausanne, Switzerland
[4] Univ Trieste, Dept Med Surg & Hlth Sci, Clin Med AOUTS, I-34142 Trieste, Italy
[5] Univ Hosp Leuven UZ Leuven, Dept & Lab Intens Care Med, B-3000 Leuven, Belgium
[6] Univ Sydney, Northern Clin Sch, Intens Care Res Unit, St Leonards, NSW 2065, Australia
[7] Univ Liverpool, Dept Med, Liverpool L69 3BX, Merseyside, England
[8] Kingston Gen Hosp, Clin Evaluat Res Unit, Kingston, ON K7L 2V7, Canada
[9] Med Univ Vienna, Div Cardiac Thorac Vasc Anesthesia & Intens Care, A-1090 Vienna, Austria
[10] Univ Milan, Dept Anesthesiol & Intens Care, I-20142 Milan, Italy
[11] Univ Roma La Sapienza, Dept Clin Med, I-00185 Rome, Italy
[12] Univ Hosp Geneva, Dept Nutr, CH-1211 Geneva, Switzerland
[13] Beilison Hosp, Dept Intens Care, IL-49100 Petah Tiqwa, Israel
[14] Karolinska Univ Hosp, Dept Anesthesiol & Intens Care Med, S-14186 Stockholm, Sweden
[15] Univ Colorado, Sch Med, Dept Anesthesiol, Aurora, CO USA
来源
CRITICAL CARE | 2015年 / 19卷
关键词
INTENSIVE-CARE-UNIT; RANDOMIZED CONTROLLED-TRIALS; PARENTERAL GLUTAMINE SUPPLEMENTATION; EARLY ENTERAL NUTRITION; SYSTEMIC INFLAMMATORY RESPONSE; TRACE-ELEMENT SUPPLEMENTATION; RESPIRATORY-DISTRESS-SYNDROME; PROLONGED CRITICAL ILLNESS; BURNED PEDIATRIC-PATIENTS; PLACEBO-CONTROLLED TRIAL;
D O I
10.1186/s13054-015-0737-8
中图分类号
R4 [临床医学];
学科分类号
1002 ; 100602 ;
摘要
The results of recent large-scale clinical trials have led us to review our understanding of the metabolic response to stress and the most appropriate means of managing nutrition in critically ill patients. This review presents an update in this field, identifying and discussing a number of areas for which consensus has been reached and others where controversy remains and presenting areas for future research. We discuss optimal calorie and protein intake, the incidence and management of re-feeding syndrome, the role of gastric residual volume monitoring, the place of supplemental parenteral nutrition when enteral feeding is deemed insufficient, the role of indirect calorimetry, and potential indications for several pharmaconutrients.
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页数:11
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