The MMSE should not be the sole indicator of fitness to drive in mild Alzheimer's dementia

被引：13

作者：

Piersma, D. ^{[1
]}

Fuermaier, A. B. M. ^{[1
]}

de Waard, D. ^{[1
]}

De Deyn, P. P. ^{[2
,3
]}

Davidse, R. J. ^{[4
]}

de Groot, J. ^{[4
]}

Doumen, M. J. A. ^{[1
,4
]}

Bredewoud, R. A. ^{[5
]}

Claesen, R. ^{[5
]}

Lemstra, A. W. ^{[6
]}

Vermeeren, A. ^{[7
]}

Ponds, R. ^{[8
]}

Verhey, F. ^{[8
]}

Brouwer, W. H. ^{[1
]}

Tucha, O. ^{[1
]}

机构：

[1] Univ Groningen, Dept Clin & Dev Neuropsychol, Groningen, Netherlands

[2] Univ Med Ctr Groningen, Dept Neurol, Groningen, Netherlands

[3] Univ Med Ctr Groningen, Alzheimer Res Ctr, Groningen, Netherlands

[4] SWOV Inst Rd Safety Res, The Hague, Netherlands

[5] CBR Dutch Driving Test Org, Rijswijk, Netherlands

[6] Vrije Univ Amsterdam, Med Ctr, Dept Neurol, Alzheimer Ctr, Amsterdam, Netherlands

[7] Maastricht Univ, Dept Neuropsychol & Psychopharmacol, Maastricht, Netherlands

[8] Maastricht Univ, Sch Mental Hlth & Neurosci MHeNS, Dept Psychiat & Neuropsychol, Maastricht, Netherlands

来源：

ACTA NEUROLOGICA BELGICA | 2018年 / 118卷 / 04期

关键词：

Alzheimer's dementia; Fitness to drive; Driving; MMSE; MINI-MENTAL-STATE; PERFORMANCE; DISEASE; CONSENSUS; SAFETY;

D O I：

10.1007/s13760-018-1036-3

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Since Alzheimer's disease may affect driving performance, patients with Alzheimer's disease are assessed on fitness to drive. On-road driving assessments are widely used, and attempts have also been made to develop strategies to assess fitness to drive in a clinical setting. Preferably, a first indication of fitness to drive is obtained quickly after diagnosis using a single test such as the Mini-Mental State Examination (MMSE). The aim of this study is to investigate whether the MMSE can be used to predict whether patients with Alzheimer's disease will pass or fail an on-road driving assessment. Patients with Alzheimer's disease (n=81) participated in a comprehensive fitness-to-drive assessment which included the MMSE as well as an on-road driving assessment [PLoS One 11(2):e0149566, 2016]. MMSE cutoffs were applied as suggested by Versijpt and colleagues [Acta Neurol Belg 117(4):811-819, 2017]. All patients with Alzheimer's disease who scored below the lower cutoff (MMSE <= 19) failed the on-road driving assessment. However, a third of the patients with Alzheimer's disease who scored above the upper cutoff (MMSE >= 25) failed the on-road driving assessment as well. We conclude that the MMSE alone has insufficient predictive value to correctly identify fitness to drive in patients with very mild-to-mild Alzheimer's disease implicating the need for comprehensive assessments to determine fitness to drive in a clinical setting.

引用

页码：637 / 642

页数：6

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