Distribution and evolution of virulence factors in septicemic Escherichia coli

被引：40
|
作者：
Ron, Eliora Z. [1 ]
机构：
[1] Tel Aviv Univ, Fac Life Sci, IL-69978 Tel Aviv, Israel
来源：
INTERNATIONAL JOURNAL OF MEDICAL MICROBIOLOGY | 2010年 / 300卷 / 06期
关键词：
Colibacillosis; Colisepticemia; Bacterial pathogenesis; Virulence factors; HIGH-PATHOGENICITY ISLAND; BLOOD-STREAM INFECTIONS; COMMUNITY-ACQUIRED BACTEREMIA; III SECRETION SYSTEM; SUBTRACTIVE HYBRIDIZATION; SHIGELLA-FLEXNERI; INVASIVE STRAINS; GENOME SEQUENCE; GENE; EPIDEMIOLOGY;
D O I：
10.1016/j.ijmm.2010.04.009
中图分类号：
Q93 [微生物学];
学科分类号：
071005 ; 100705 ;
摘要：
Bacterial septicemia is an emerging clinical problem which is increasing in significance due to the rapid spread of antibiotic resistance. In order to combat this problem, it is essential to identify the critical virulence factors of these septicemic strains and study their functions and role in pathogenesis. Here, we survey some of the virulence factors which are essential for sepsis and are potential candidates for development of new drugs or vaccines. (C) 2010 Elsevier GmbH. All rights reserved.
引用
收藏
页码：367 / 370
页数：4
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