Quality of Life (QOL) of patients with Gilles de la Tourette's syndrome

被引:119
作者
Elstner, K
Selai, CE
Trimble, MR
Robertson, MM
机构
[1] Natl Hosp Neurol & Neurosurg, Inst Neurol, MSC Clin Neurosci & Honorary Res, London WC1N 3BG, England
[2] Royal Cornwall Hosp, Truro, Cornwall, England
[3] Inst Neurol, Raymond Way Neuropsychiat Unit, London WC1N 3BG, England
[4] UCL, Sch Med, London W1N 8AA, England
关键词
Gilles de la Tourette's Syndrome; health status; quality of life; psychopathology;
D O I
10.1034/j.1600-0447.2001.00147.x
中图分类号
R749 [精神病学];
学科分类号
100205 ;
摘要
Objective: This is the first study to investigate the Quality of Life (QOL) of patients with Gilles de la Tourette's Syndrome (GTS). Method: One hundred and three out-patients with GTS completed a semi-structured interview and 90 of these completed questionnaires screening for depression, anxiety and obsessive-compulsive behaviour. QOL was measured with the SF-36 and the Quality of Life Assessment Schedule (QOLAS). Results: Patients with GTS showed significantly worse QOL than a general population sample. They had better QOL than patients with intractable epilepsy as measured by the QOLAS, although the SF-36 showed significant differences on the subscales Role Limitation due to physical problems and Social Functioning only. Factors influencing QOL domains were employment status, tic severity, obsessive-compulsive behaviour, anxiety and depression. Conclusion: QOL is impaired in patients with GTS. Measurement of QOL could be used alongside conventional measurements to assess benefit of treatment. We recommend the QOLAS and SF-36 be used.
引用
收藏
页码:52 / 59
页数:8
相关论文
共 34 条
[21]  
ROBERTSON MM, 1995, J SEROTONIN RES S, V1, P49
[22]  
SELAI C, 1988, SEIZURE, V7, P1
[23]  
SELAI C, 2000, IN PRESS NEUROPSYCHO
[24]  
Selai CE, 2000, EPILEPSY RES, V38, P67
[25]  
SELAI CE, 1999, QUALITY LIFE ASSESSM
[26]   COMPARISON OF WRITTEN AND POSTBOX FORMS OF THE LEYTON OBSESSIONAL INVENTORY [J].
SNOWDON, J .
PSYCHOLOGICAL MEDICINE, 1980, 10 (01) :165-170
[27]  
SPIELBERGER CD, 1983, MANUAL STATE TRAIT A
[28]  
*SPSS INC, SPSS BAS SYST US GUI
[29]  
STEER RA, 1982, ASSESSMENT DEPRESSIO, P123
[30]   MENTAL-HEALTH NEEDS ASSOCIATED WITH TOURETTE SYNDROME [J].
STEFL, ME .
AMERICAN JOURNAL OF PUBLIC HEALTH, 1984, 74 (12) :1310-1313