Automatic measurement and analysis of neonatal O-2 consumption and CO2 production

It is difficult to estimate daily energy expenditure unless continuous O-2 consumption (V-O2) and CO2 production (V-CO2) can be measured. This study describes a simple method for calculating daily and interim changes in O-2 consumption and CO2 production for neonates, especially for premature infants. Oxygen consumption and CO2 production are measured using a flow-through technique in which the total V-O2 and V-CO2 over a given period of time are determined through a computerized system. This system can automatically calculate V-O2 and V-CO2 not only minute to minute but also over a period of time, e.g., 24 h. As a result, it provides a better indirect reflection of the accurate energy expenditure in an infant's daily life and can be used at the bedside of infants during their ongoing nursery care. (C) 1996 American Institute of Physics.