Vemurafenib Response in 2 Patients With Posttransplant Refractory BRAF V600E-Mutated Multiple Myeloma

被引：38

作者：

Sharman, J. P. ^{[1
]}

Chmielecki, J. ^{[2
]}

Morosini, D. ^{[2
]}

Palmer, G. A. ^{[2
]}

Ross, J. S. ^{[2
,3
]}

Stephens, P. J. ^{[2
]}

Stafl, J. ^{[1
]}

Miller, V. A. ^{[2
]}

Ali, S. M. ^{[2
]}

机构：

[1] Willamette Valley Canc Inst, Eugene, OR USA

[2] Fdn Med Inc, Cambridge, MA USA

[3] Albany Med Coll, Albany, NY 12208 USA

来源：

CLINICAL LYMPHOMA MYELOMA & LEUKEMIA | 2014年 / 14卷 / 05期

关键词：

Mitogen-activated protein kinase; Mutation; Refractory myeloma; Vemurafenib; V600E;

D O I：

10.1016/j.clml.2014.06.004

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

[No abstract available]

引用

页码：E161 / E163

页数：3

共 6 条

[1] Targeting the BRAF V600E Mutation in Multiple Myeloma [J].

Andrulis, Mindaugas ;

Lehners, Nicola ;

Capper, David ;

Penzel, Roland ;

Heining, Christoph ;

Huellein, Jennifer ;

Zenz, Thorsten ;

von Deimling, Andreas ;

Schirmacher, Peter ;

Ho, Anthony D. ;

Goldschmidt, Hartmut ;

Neben, Kai ;

Raab, Marc S. .

CANCER DISCOVERY, 2013, 3 (08) :862-869

[2]

Bohn Olga L, 2014, Clin Lymphoma Myeloma Leuk, V14, pe65, DOI 10.1016/j.clml.2013.12.003

[3] Initial genome sequencing and analysis of multiple myeloma [J].

Chapman, Michael A. ;

Lawrence, Michael S. ;

Keats, Jonathan J. ;

Cibulskis, Kristian ;

Sougnez, Carrie ;

Schinzel, Anna C. ;

Harview, Christina L. ;

Brunet, Jean-Philippe ;

Ahmann, Gregory J. ;

Adli, Mazhar ;

Anderson, Kenneth C. ;

Ardlie, Kristin G. ;

Auclair, Daniel ;

Baker, Angela ;

Bergsagel, P. Leif ;

Bernstein, Bradley E. ;

Drier, Yotam ;

Fonseca, Rafael ;

Gabriel, Stacey B. ;

Hofmeister, Craig C. ;

Jagannath, Sundar ;

Jakubowiak, Andrzej J. ;

Krishnan, Amrita ;

Levy, Joan ;

Liefeld, Ted ;

Lonial, Sagar ;

Mahan, Scott ;

Mfuko, Bunmi ;

Monti, Stefano ;

Perkins, Louise M. ;

Onofrio, Robb ;

Pugh, Trevor J. ;

Rajkumar, S. Vincent ;

Ramos, Alex H. ;

Siegel, David S. ;

Sivachenko, Andrey ;

Stewart, A. Keith ;

Trudel, Suzanne ;

Vij, Ravi ;

Voet, Douglas ;

Winckler, Wendy ;

Zimmerman, Todd ;

Carpten, John ;

Trent, Jeff ;

Hahn, William C. ;

Garraway, Levi A. ;

Meyerson, Matthew ;

Lander, Eric S. ;

Getz, Gad ;

Golub, Todd R. .

NATURE, 2011, 471 (7339) :467-472

[4] Widespread Genetic Heterogeneity in Multiple Myeloma: Implications for Targeted Therapy [J].

Lohr, Jens G. ;

Stojanov, Petar ;

Carter, Scott L. ;

Cruz-Gordillo, Peter ;

Lawrence, Michael S. ;

Auclair, Daniel ;

Sougnez, Carrie ;

Knoechel, Birgit ;

Gould, Joshua ;

Saksena, Gordon ;

Cibulskis, Kristian ;

McKenna, Aaron ;

Chapman, Michael A. ;

Straussman, Ravid ;

Levy, Joan ;

Perkins, Louise M. ;

Keats, Jonathan J. ;

Schumacher, Steven E. ;

Rosenberg, Mara ;

Getz, Gad ;

Golub, Todd R. .

CANCER CELL, 2014, 25 (01) :91-101

[5] BRAF - A new player in hematological neoplasms [J].

Machnicki, Marcin M. ;

Stoklosa, Tomasz .

BLOOD CELLS MOLECULES AND DISEASES, 2014, 53 (1-2) :77-83

[6] B-Raf mutation: A key player in molecular biology of cancer [J].

Rahman, M. A. ;

Salajegheh, A. ;

Smith, R. A. ;

Lam, A. K. -Y. .

EXPERIMENTAL AND MOLECULAR PATHOLOGY, 2013, 95 (03) :336-342

← 1 →