Tautomeric changes in guanfacine and its copper(II) complex as revealed by X-ray crystallography; synthesis and EPR

被引：6
作者：
Tomas, A
Viossat, B
Charlot, MF
Girerd, JJ
Huy, DN
机构：
[1] Fac Pharm, UMR 8015, Lab Cristallog & RMN Biol, F-75270 Paris, France
[2] Univ Paris 11, Chim Inorgan Lab, UMR 8613, F-91405 Orsay, France
[3] Lab Cristallochim Bioinorgan, F-92296 Chatenay Malabry, France
来源：
INORGANICA CHIMICA ACTA | 2005年 / 358卷 / 11期
关键词：
copper(II) complex; crystal structure; EPR analysis; guanfacine; tautomeric forms;
D O I：
10.1016/j.ica.2005.03.040
中图分类号：
O61 [无机化学];
学科分类号：
070301 ; 081704 ;
摘要：
Obtention and crystal structure of guanfacine (guaH) together with synthesis and crystal structure of its copper complex [Cu-II(gua)(2)] center dot DMF were reported. The free molecule guaH exhibits one tautomeric form (B) in contrast to the form (A) which was reported in the Merck index. In the copper(II) complex, the anionic form gua(-) exhibits the third tautomeric form (C). This complex is characterized by a CuN2O2 coordination. The EPR spectrum is in agreement with a Cu(II) ion in a square planar configuration. (c) 2005 Elsevier B.V. All rights reserved.
引用
收藏
页码：3253 / 3258
页数：6
相关论文
共 50 条
[31]   Synthesis and X-ray structural characterization of Cobalt(II), Copper(II), and Silver(I) complexes of triphenylphosphoniopropionate [J].
Li, SL ;
Mak, TCW .
STRUCTURAL CHEMISTRY, 1997, 8 (01) :49-63
[32]   Application of X-ray Diffraction and Electron Crystallography for Solving Complex Structure Problems [J].
Li, Jian ;
Sun, Junliang .
ACCOUNTS OF CHEMICAL RESEARCH, 2017, 50 (11) :2737-2745
[33]   Synthesis and X-ray structural characterization of cobalt(II), copper(II), and silver(I) complexes of triphenylphosphoniopropionate [J].
Song -Lin Li ;
Thomas C. W. Mak .
Structural Chemistry, 1997, 8 :49-63
[34]   Unusual saccharin-N,O (carbonyl) coordination in mixed-ligand copper(II) complexes: Synthesis, X-ray crystallography and biological activity [J].
Mokhtaruddin, Nur Shuhada Mohd ;
Yusof, Enis Nadia Md ;
Ravoof, Thahira B. S. A. ;
Tiekink, Edward R. T. ;
Veerakumarasivam, Abhi ;
Tahir, Mohamed Ibrahim Mohamed .
JOURNAL OF MOLECULAR STRUCTURE, 2017, 1139 :1-9
[35]   Synthesis and Characterization of Some New Binary and Ternary Copper Complexes: X-Ray Crystal Structural of Dioxo Dinuclear Bipyridine Copper Complex [J].
Ramadan, Ramadan M. ;
Shohayeb, Shahera M. ;
Mohamed, Rania G. .
SYNTHESIS AND REACTIVITY IN INORGANIC METAL-ORGANIC AND NANO-METAL CHEMISTRY, 2013, 43 (05) :609-616
[36]   Epitope-dependent mechanisms of CD27 neutralization revealed by X-ray crystallography [J].
Obmolova, Galina ;
Teplyakov, Alexey ;
Malia, Thomas J. ;
Wunderler, Nicole ;
Kwok, Deborah ;
Barone, Linda ;
Sweet, Raymond ;
Ort, Tatiana ;
Scully, Michael ;
Gilliland, Gary L. .
MOLECULAR IMMUNOLOGY, 2017, 83 :92-99
[37]   Microcrystal preparation for serial femtosecond X-ray crystallography of bacterial copper amine oxidase [J].
Murakawa, Takeshi ;
Suzuki, Mamoru ;
Arima, Toshi ;
Sugahara, Michihiro ;
Tanaka, Tomoyuki ;
Tanaka, Rie ;
Iwata, So ;
Nango, Eriko ;
Tono, Kensuke ;
Hayashi, Hideyuki ;
Fukui, Kenji ;
Yano, Takato ;
Tanizawa, Katsuyuki ;
Okajima, Toshihide .
ACTA CRYSTALLOGRAPHICA SECTION F-STRUCTURAL BIOLOGY COMMUNICATIONS, 2021, 77 :356-363
[38]   Copper(II) and cobalt(II) complexes of 5-methyl pyrazole-3-carboxylic acid: synthesis, X-ray crystallography, thermal analysis and in vitro antimicrobial activity [J].
Santra, Ananyakumari ;
Brandao, Paula ;
Jana, Harekrishna ;
Mondal, Gopinath ;
Bera, Pradip ;
Jana, Abhimanyu ;
Bera, Pulakesh .
JOURNAL OF COORDINATION CHEMISTRY, 2018, 71 (22) :3648-3664
[39]   Synthesis, X-ray structures and cytotoxic activity of platinum(II), palladium(II) and copper(II) complexes with chelating ligands [J].
Budzisz, Elzbieta ;
Miernicka, Magdalena ;
Lorenz, Ingo-Peter ;
Mayer, Peter ;
Balcerczak, Ewa ;
Krajewska, Urszula ;
Rozalski, Marek .
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2010, 45 (06) :2613-2621
[40]   Synthesis and X-ray crystallography of bipyrroles: impacts of a CO-π interaction on their structure [J].
Okawara, Toru ;
Doi, Akane ;
Ono, Toshikazu ;
Abe, Masaaki ;
Takehara, Kenji ;
Hisaeda, Yoshio ;
Matsushima, Shigenori .
TETRAHEDRON LETTERS, 2015, 56 (11) :1407-1410
12345