The prevalence of Myocardial Infarction among Multiple Sclerosis Patients: a Systematic Review and Meta-analysis

被引：5

作者：

Tavallaei, Mohammad Javad ^{[1
]}

Tavallaei, Amir Hossein ^{[2
]}

Ebrahimi, Narges ^{[3
]}

Ghoshouni, Hamed ^{[4
]}

Afshari-Safavi, Alireza ^{[5
]}

Badihian, Shervin ^{[6
]}

Shaygannejad, Vahid ^{[3
,7
]}

Mirmosayyeb, Omid ^{[3
,7
]}

机构：

[1] Iran Univ Med Sci, Sch Med, Tehran, Iran

[2] Univ Tehran Med Sci, Sch Med, Tehran, Iran

[3] Isfahan Univ Med Sci, Isfahan Neurosci Res Ctr, Esfahan, Iran

[4] Shahid Sadoughi Univ Med Sci, Sch Med, Yazd, Iran

[5] North Khorasan Univ Med Sci, Fac Hlth, Dept Biostat & Epidemiol, Bojnurd, Iran

[6] Johns Hopkins Univ, Sch Med, Dept Neurol, Baltimore, MD USA

[7] Isfahan Univ Med Sci, Dept Neurol, Esfahan, Iran

来源：

MULTIPLE SCLEROSIS AND RELATED DISORDERS | 2021年 / 56卷

关键词：

Myocardial Infarction; Multiple Sclerosis; systematic review; meta-analysis; prevalence; PRACTICE RESEARCH DATABASE; CARDIOVASCULAR-DISEASES; VASCULAR-DISEASE; RISK; COMORBIDITIES; POPULATION; MORTALITY; SURVIVAL; MS; ADMISSION;

D O I：

10.1016/j.msard.2021.103292

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Background: People with multiple sclerosis (PwMS) are suggested to have a higher death rate compared to the overall population. Increased risk and incidence of cardiovascular diseases is a possible contributing factor here, as these patients are suggested to be more prone to early death due to myocardial infarction (MI). Aim: This systematic review aims to describe the prevalence of MI among PwMS in comparison to the non-MS population. Method: We thoroughly searched for publications reporting the prevalence of MI among PwMS in PubMed, Scopus, Embase, and Web of Science. We excluded studies focusing on the following conditions: ischemic heart disease only, autopsy of PwMS, MS patients with a previous history of cardiovascular diseases, and MS diagnosed after MI. Moreover, we excluded reviews, editorials, and commentaries. We used the random effect model to calculate the pooled prevalence. Results: We included nineteen studies, comprising 44 to 66616 participants. The overall prevalence of MI was 1.7% among PwMS. The pooled odds ratio estimate for MI was 1.41 in PwMS compared to the MS-free population. Conclusions: Results of this systematic review confirms the increased risk of MI among PwMS. Consequently, cardiovascular diseases should be considered in the management of these patients.

引用

页数：6