Alternative reaction conditions: Enabling technologies in solvent-free protocols

被引：21

作者：

Cintas, Pedro ^{[1
,2
]}

Tabasso, Silvia ^{[3
]}

Veselov, Valery V. ^{[4
]}

Cravotto, Giancarlo ^{[5
]}

机构：

[1] Univ Extremadura, Dept Quim Organ & Inorgan, Fac Ciencias, Badajoz 06006, Spain

[2] Univ Extremadura, IACYS Unidad Quim Verde & Desarrollo Sostenible, Badajoz 06006, Spain

[3] Univ Turin, Dipartimento Chim, Via P Giuria 7, I-10125 Turin, Italy

[4] Sechenov First Moscow State Med Univ, Ctr Bioanalyt Res & Mol Design, 8 Trubetskaya Ul, Moscow, Russia

[5] Univ Turin, Dipartimento Sci & Tecnol Farmaco, Via Pietro Giuria 9, I-10125 Turin, Italy

来源：

CURRENT OPINION IN GREEN AND SUSTAINABLE CHEMISTRY | 2020年 / 21卷

关键词：

ORGANIC-SYNTHESIS; MECHANOCHEMISTRY;

D O I：

10.1016/j.cogsc.2019.11.007

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Solventless and solid-state reactions have become increasingly popular and appealing options in the field of green chemistry and process intensification as they can often minimise waste and energy costs. A variety of strategies and protocols (in particular ball milling, dielectric heating and reactive extrusion) have been developed and improved over the last two decades. Although this account cannot be comprehensive, it will, however, provide a glimpse of such methods, highlight the advantages and limitations of strategies and discuss some mechanistic considerations. A few examples for each case, often from our own laboratories, will be used to illustrate specific applications.

引用

页码：44 / 49

页数：6

共 30 条

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[2]

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