Pulmonary embolism, spontaneous pneumomediastinum and subcutaneous emphysema in a patient with COVID-19 disease: A case report

被引：0

作者：

Moumtzi, Despoina ^{[1
]}

Gavriilidou, Anna ^{[1
]}

Gasteratos, Konstantinos ^{[2
]}

Vlachakis, Dimitrios ^{[3
]}

Kakoura, Marianna ^{[1
]}

机构：

[1] Papageorgiou Gen Hosp, Resp Dept, Thessaloniki 56429, Greece

[2] Papageorgiou Gen Hosp, Plast & Reconstruct Surg Dept, Thessaloniki, Greece

[3] Papageorgiou Gen Hosp, Dept Internal Med 1, Thessaloniki, Greece

来源：

PNEUMON | 2021年 / 34卷 / 04期

关键词：

COVID-19; pulmonary embolism; pneumomediastinum; subcutaneous emphysema;

D O I：

10.18332/pne/143223

中图分类号：

R56 [呼吸系及胸部疾病];

学科分类号：

摘要：

The pathophysiology of pulmonary embolism (PE) and pneumomediastinum (PNM) in COVID-19 patients remain unclear. Studies indicate that the infection of the endothelial cells by the virus perpetuates a storm of cytokines and thrombogenic factors, which cause endothelium injury. We present a unique, to our knowledge, case of a patient aged 56 years with COVID-19 pneumonia who was admitted with dyspnea, desaturation, and fever. His situation was complicated by both PNM and PE. He received appropriate treatment with a therapeutic dose of low molecular weight heparin, and exhibited clinical improvement and resolution of the subcutaneous emphysema. Clinicians should suspect both PE and PNM within the differential diagnosis in cases of COVID-19 patients with pleuritic pain, dyspnea, and respiratory failure, after the tenth day from the onset of symptoms.

引用

页数：5

共 15 条

[1] MRSA infections among patients in the emergency department: a European multicentre study [J].

Bouchiat, C. ;

Curtis, S. ;

Spiliopoulou, I. ;

Bes, M. ;

Cocuzza, C. ;

Codita, I. ;

Dupieux, C. ;

Giormezis, N. ;

Kearns, A. ;

Laurent, F. ;

Molinos, S. ;

Musumeci, R. ;

Prat, C. ;

Saadatian-Elahi, M. ;

Tacconelli, E. ;

Tristan, A. ;

Schulte, B. ;

Vandenesch, F. .

JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY, 2017, 72 (02) :372-375

[2] Systemic endothelial dysfunction: A common pathway for COVID-19, cardiovascular and metabolic diseases [J].

De Lorenzo, Andrea ;

Escobar, Silas ;

Tibirica, Eduardo .

NUTRITION METABOLISM AND CARDIOVASCULAR DISEASES, 2020, 30 (08) :1401-1402

[3] Acute Pulmonary Embolism Associated with COVID-19 Pneumonia Detected with Pulmonary CT Angiography [J].

Grillet, Franck ;

Behr, Julien ;

Calame, Paul ;

Aubry, Sebastien ;

Delabrousse, Eric .

RADIOLOGY, 2020, 296 (03) :E186-E188

[4] Spontaneous pneumomediastinum, pneumopericardium, pneumothorax and subcutaneous emphysema in patients with COVID-19 pneumonia, a case report [J].

Hazariwala, Vikisha ;

Hadid, Hind ;

Kirsch, Denise ;

Big, Cecilia .

JOURNAL OF CARDIOTHORACIC SURGERY, 2020, 15 (01)

[5] Bacterial and fungal coinfection among hospitalized patients with COVID-19: a retrospective cohort study in a UK secondary-care setting [J].

Hughes, S. ;

Troise, O. ;

Donaldson, H. ;

Mughal, N. ;

Moore, L. S. P. .

CLINICAL MICROBIOLOGY AND INFECTION, 2020, 26 (10) :1395-1399

[6] Acute Pulmonary Embolism in Patients with COVID-19 at CT Angiography and Relationship to D-Dimer Levels [J].

Leonard-Lorant, Ian ;

Delabranche, Xavier ;

Severac, Francois ;

Helms, Julie ;

Pauzet, Coralie ;

Collange, Olivier ;

Schneider, Francis ;

Labani, Aissam ;

Bilbault, Pascal ;

Moliere, Sebastien ;

Leyendecker, Pierre ;

Roy, Catherine ;

Ohana, Mickael .

RADIOLOGY, 2020, 296 (03) :E189-E191

[7] Incidence and mortality of pulmonary embolism in COVID-19: a systematic review and meta-analysis [J].

Liao, Shu-Chen ;

Shao, Shih-Chieh ;

Chen, Yih-Ting ;

Chen, Yung-Chang ;

Hung, Ming-Jui .

CRITICAL CARE, 2020, 24 (01)

[8] Diagnosis, Prevention, and Treatment of Thromboembolic Complications in COVID-19: Report of the National Institute for Public Health of the Netherlands [J].

Oudkerk, Matthijs ;

Buller, Harry R. ;

Kuijpers, Dirkjan ;

van Es, Nick ;

Oudkerk, Sytse F. ;

McLoud, Theresa ;

Gommers, Diederik ;

van Dissel, Jaap ;

ten Cate, Hugo ;

van Beek, Edwin J. R. .

RADIOLOGY, 2020, 297 (01) :E216-E222

[9] Diagnosis, Management, and Pathophysiology of Arterial and Venous Thrombosis in COVID-19 [J].

Piazza, Gregory ;

Morrow, David A. .

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 2020, 324 (24) :2548-2549

[10] Pulmonary Embolism in Patients With COVID-19 Awareness of an Increased Prevalence [J].

Poissy, Julien ;

Goutay, Julien ;

Caplan, Morgan ;

Parmentier, Erika ;

Duburcq, Thibault ;

Lassalle, Fanny ;

Jeanpierre, Emmanuelle ;

Rauch, Antoine ;

Labreuche, Julien ;

Susen, Sophie .

CIRCULATION, 2020, 142 (02) :184-186

← 1 2 →