Pulmonary embolism, spontaneous pneumomediastinum and subcutaneous emphysema in a patient with COVID-19 disease: A case report

被引：0
作者：
Moumtzi, Despoina [1 ]
Gavriilidou, Anna [1 ]
Gasteratos, Konstantinos [2 ]
Vlachakis, Dimitrios [3 ]
Kakoura, Marianna [1 ]
机构：
[1] Papageorgiou Gen Hosp, Resp Dept, Thessaloniki 56429, Greece
[2] Papageorgiou Gen Hosp, Plast & Reconstruct Surg Dept, Thessaloniki, Greece
[3] Papageorgiou Gen Hosp, Dept Internal Med 1, Thessaloniki, Greece
来源：
PNEUMON | 2021年 / 34卷 / 04期
关键词：
COVID-19; pulmonary embolism; pneumomediastinum; subcutaneous emphysema;
D O I：
10.18332/pne/143223
中图分类号：
R56 [呼吸系及胸部疾病];
学科分类号：
摘要：
The pathophysiology of pulmonary embolism (PE) and pneumomediastinum (PNM) in COVID-19 patients remain unclear. Studies indicate that the infection of the endothelial cells by the virus perpetuates a storm of cytokines and thrombogenic factors, which cause endothelium injury. We present a unique, to our knowledge, case of a patient aged 56 years with COVID-19 pneumonia who was admitted with dyspnea, desaturation, and fever. His situation was complicated by both PNM and PE. He received appropriate treatment with a therapeutic dose of low molecular weight heparin, and exhibited clinical improvement and resolution of the subcutaneous emphysema. Clinicians should suspect both PE and PNM within the differential diagnosis in cases of COVID-19 patients with pleuritic pain, dyspnea, and respiratory failure, after the tenth day from the onset of symptoms.
引用
收藏
页数：5
相关论文
共 15 条
  • [1] MRSA infections among patients in the emergency department: a European multicentre study
    Bouchiat, C.
    Curtis, S.
    Spiliopoulou, I.
    Bes, M.
    Cocuzza, C.
    Codita, I.
    Dupieux, C.
    Giormezis, N.
    Kearns, A.
    Laurent, F.
    Molinos, S.
    Musumeci, R.
    Prat, C.
    Saadatian-Elahi, M.
    Tacconelli, E.
    Tristan, A.
    Schulte, B.
    Vandenesch, F.
    [J]. JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY, 2017, 72 (02) : 372 - 375
  • [2] Systemic endothelial dysfunction: A common pathway for COVID-19, cardiovascular and metabolic diseases
    De Lorenzo, Andrea
    Escobar, Silas
    Tibirica, Eduardo
    [J]. NUTRITION METABOLISM AND CARDIOVASCULAR DISEASES, 2020, 30 (08) : 1401 - 1402
  • [3] Acute Pulmonary Embolism Associated with COVID-19 Pneumonia Detected with Pulmonary CT Angiography
    Grillet, Franck
    Behr, Julien
    Calame, Paul
    Aubry, Sebastien
    Delabrousse, Eric
    [J]. RADIOLOGY, 2020, 296 (03) : E186 - E188
  • [4] Spontaneous pneumomediastinum, pneumopericardium, pneumothorax and subcutaneous emphysema in patients with COVID-19 pneumonia, a case report
    Hazariwala, Vikisha
    Hadid, Hind
    Kirsch, Denise
    Big, Cecilia
    [J]. JOURNAL OF CARDIOTHORACIC SURGERY, 2020, 15 (01)
  • [5] Bacterial and fungal coinfection among hospitalized patients with COVID-19: a retrospective cohort study in a UK secondary-care setting
    Hughes, S.
    Troise, O.
    Donaldson, H.
    Mughal, N.
    Moore, L. S. P.
    [J]. CLINICAL MICROBIOLOGY AND INFECTION, 2020, 26 (10) : 1395 - 1399
  • [6] Acute Pulmonary Embolism in Patients with COVID-19 at CT Angiography and Relationship to D-Dimer Levels
    Leonard-Lorant, Ian
    Delabranche, Xavier
    Severac, Francois
    Helms, Julie
    Pauzet, Coralie
    Collange, Olivier
    Schneider, Francis
    Labani, Aissam
    Bilbault, Pascal
    Moliere, Sebastien
    Leyendecker, Pierre
    Roy, Catherine
    Ohana, Mickael
    [J]. RADIOLOGY, 2020, 296 (03) : E189 - E191
  • [7] Incidence and mortality of pulmonary embolism in COVID-19: a systematic review and meta-analysis
    Liao, Shu-Chen
    Shao, Shih-Chieh
    Chen, Yih-Ting
    Chen, Yung-Chang
    Hung, Ming-Jui
    [J]. CRITICAL CARE, 2020, 24 (01):
  • [8] Diagnosis, Prevention, and Treatment of Thromboembolic Complications in COVID-19: Report of the National Institute for Public Health of the Netherlands
    Oudkerk, Matthijs
    Buller, Harry R.
    Kuijpers, Dirkjan
    van Es, Nick
    Oudkerk, Sytse F.
    McLoud, Theresa
    Gommers, Diederik
    van Dissel, Jaap
    ten Cate, Hugo
    van Beek, Edwin J. R.
    [J]. RADIOLOGY, 2020, 297 (01) : E216 - E222
  • [9] Diagnosis, Management, and Pathophysiology of Arterial and Venous Thrombosis in COVID-19
    Piazza, Gregory
    Morrow, David A.
    [J]. JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 2020, 324 (24): : 2548 - 2549
  • [10] Pulmonary Embolism in Patients With COVID-19 Awareness of an Increased Prevalence
    Poissy, Julien
    Goutay, Julien
    Caplan, Morgan
    Parmentier, Erika
    Duburcq, Thibault
    Lassalle, Fanny
    Jeanpierre, Emmanuelle
    Rauch, Antoine
    Labreuche, Julien
    Susen, Sophie
    [J]. CIRCULATION, 2020, 142 (02) : 184 - 186
12