Radiomics and radiogenomics in head and neck squamous cell carcinoma: Potential contribution to patient management and challenges

被引:36
作者
Bruixola, Gema [1 ]
Remacha, Elena [2 ]
Jimenez-Pastor, Ana [2 ]
Dualde, Delfina [3 ]
Viala, Alba [1 ]
Monton, Jose Vicente [1 ,4 ]
Ibarrola-Villava, Maider [1 ]
Alberich-Bayarri, Angel [2 ]
Cervantes, Andres [4 ,5 ]
机构
[1] Univ Valencia, INCLIVA Biomed Res Inst, Dept Med Oncol, Valencia, Spain
[2] Quantitat Imaging Biomarkers Med QUIBIM SL, Edificio Europa,Av Aragon,30,Planta 12, Valencia 46021, Spain
[3] Univ Valencia, INCLIVA Biomed Res Inst, Dept Radiol, Valencia, Spain
[4] Inst Salud Carlos III, CIBERONC, Madrid, Spain
[5] Univ Valencia, INCLIVA Biomed Res Inst, Dept Med Oncol, Blasco Ibanez 17, Valencia 46010, Spain
关键词
Radiomics; Head and neck cancer; Imaging biomarkers; Prognostic biomarkers; Molecular subtypes; Machine learning; LOCALLY ADVANCED HEAD; APPARENT DIFFUSION-COEFFICIENT; HUMAN-PAPILLOMAVIRUS STATUS; AMERICAN JOINT COMMITTEE; TEXTURE ANALYSIS; PROGNOSTIC VALUE; IMAGING BIOMARKERS; RADIATION-THERAPY; ORAL-CAVITY; OROPHARYNGEAL;
D O I
10.1016/j.ctrv.2021.102263
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
The application of imaging biomarkers in oncology is still in its infancy, but with the expansion of radiomics and radiogenomics a revolution is expected in this field. This may be of special interest in head and neck cancer, since it can promote precision medicine and personalization of treatment by overcoming several intrinsic obstacles in this pathology. Our goal is to provide the medical oncologist with the basis to approach these disciplines and appreciate their main uses in clinical research and clinical practice in the medium term. Aligned with this objective we analyzed the most relevant studies in the field, also highlighting novel opportunities and current challenges.
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页数:13
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