A multicenter, case-control study on risk factors for antepartum stillbirth

被引:29
|
作者
Facchinetti, Fabio [1 ]
Alberico, Salvatore [2 ]
Benedetto, Chiara [3 ]
Cetin, Irene [4 ]
Cozzolino, Sabrina [5 ]
Di Renzo, Gian Carlo [6 ]
Del Giovane, Cinzia [7 ]
Ferrari, Francesca [1 ]
Mecacci, Federico [8 ]
Menato, Guido [9 ]
Tranquilli, Andrea L. [10 ]
Baronciani, Dante [11 ]
机构
[1] Univ Modena & Reggio Emilia, Mother Infant Dept, Modena, Italy
[2] IRCCS Burlo Garofalo, Dept Obstet & Gynecol, Trieste, Italy
[3] Univ Turin, Dept Obstet & Gynecol, Turin, Italy
[4] Univ Milan, DISG Luigi Sacco, Milan, Italy
[5] Univ Milano Bicocca, Obstet & Gynecol Unit, Monza, Italy
[6] Univ Perugia, Ctr Perinatal & Reprod Med, I-06100 Perugia, Italy
[7] Univ Modena & Reggio Emilia, Dept Oncol Hematol & Resp Dis, Modena, Italy
[8] Univ Florence, Dept Obstet & Gynecol, Florence, Italy
[9] Univ Turin, Obstet & Gynecol Chair A, Turin, Italy
[10] Marche Polytech Univ, Ancona, Italy
[11] AUSL Modena, Ctr Evaluat Effectiveness Hlth Care, Modena, Italy
关键词
Stillbirth; risk factors; preeclampsia; IUGR; obesity; FETAL-DEATH; PERINATAL-MORTALITY; CLASSIFICATION; PREGNANCY; OUTCOMES; PREVENTION; MANAGEMENT; WEIGHT;
D O I
10.3109/14767058.2010.496880
中图分类号
R71 [妇产科学];
学科分类号
100211 ;
摘要
Study design. aEuro integral Multivariate logistic regression analysis (OR with 95%% CI) was utilized in a prospective multicentre nested case--control study to compare in a 1:2 ratio stillborn of > 22 weeks gestation with matched for gestational age live-born (LB) infants. Intrapartum SB were excluded. Results. aEuro integral Two hundred fifty-four consecutive SBs and 497 LBs were enrolled. Socio-demographic variables were equally distributed. Fetal malformations (7.96, 2.69--23.55), severe intrauterine growth restriction (IUGR) (birthweight < a parts per thousand currency sign5<SUth</SU %%ile) (4.32, 2.27--8.24), BMI > 25 (2.87, 1.90--4.33), and preeclampsia (PE, 0.40, 0.21--0.77) were recognized as independent predictors for SB. At term, only BMI > 25 was associated with SB (7.70, 2.9--20.5). Conclusion. aEuro integral Fetal malformations, severe IUGR and maternal BMI > 25 were associated with a significant increase in the risk of SB; PE presented instead a protective role. Maternal BMI > 25 was the only risk factor for SB identified in term pregnancies.
引用
收藏
页码:407 / 410
页数:4
相关论文
共 50 条
  • [21] Risk Factors Associated with Lipomyelomeningocele: A Case-Control Study
    Esmaeili, Arash
    Hanaei, Sara
    Fadakar, Kaveh
    Dadkhah, Sahar
    Arjipour, Mahdi
    Habibi, Zohreh
    Nejat, Farideh
    El Khashab, Mostafa
    PEDIATRIC NEUROSURGERY, 2013, 49 (04) : 202 - 207
  • [22] Prepregnancy Risk Factors for Antepartum Stillbirth in the United States
    Reddy, Uma M.
    Laughon, S. Katherine
    Sun, Liping
    Troendle, James
    Willinger, Marian
    Zhang, Jun
    OBSTETRICS AND GYNECOLOGY, 2010, 116 (05) : 1119 - 1126
  • [23] Risk Factors for Stillbirth: Findings from a Population-Based Case-Control Study, Haryana, India
    Neogi, Sutapa Bandyopadhyay
    Negandhi, Preeti
    Chopra, Sapna
    Das, Ankan Mukherjee
    Zodpey, Sanjay
    Gupta, Ravi Kant
    Gupta, Rakesh
    PAEDIATRIC AND PERINATAL EPIDEMIOLOGY, 2016, 30 (01) : 56 - 66
  • [24] Risk Factors for Necrotizing Enterocolitis: A Prospective Multicenter Case-Control Study
    Berkhout, Daniel J. C.
    Klaassen, Patrick
    Niemarkt, Hendrik J.
    de Boode, Willem P.
    Cossey, Veerle
    van Goudoever, Johannes B.
    Hulzebos, Christiaan V.
    Andriessen, Peter
    van Kaam, Anton H.
    Kramer, Boris W.
    van Lingen, Richard A.
    Vijlbrief, Daniel C.
    van Weissenbruch, Mirjam M.
    Benninga, Marc
    de Boer, Nanne K. H.
    de Meij, Tim G. J.
    NEONATOLOGY, 2018, 114 (03) : 277 - 284
  • [25] Maternal and fetal risk factors for stillbirth in Otjozondjupa Region, Namibia: a case control study
    Shikesho, Rebekka Ndatolewe
    Amakali-Nauiseb, Taimi
    Nyarko, Kofi Mensah
    PAN AFRICAN MEDICAL JOURNAL, 2023, 44
  • [26] Environmental Risk Factors in Pediatric Psoriasis: A Multicenter Case-Control Study
    Ozden, Muge G.
    Tekin, Nilgun S.
    Gurer, Mehmet A.
    Akdemir, Devrim
    Dogramaci, Cigdem
    Utas, Serap
    Akman, Ayse
    Evans, Sibel E.
    Bahadir, Sevgi
    Ozturkcan, Serap
    Ikizoglu, Guliz
    Sendur, Neslihan
    Kose, Osman
    Bek, Yuksel
    Yayli, Savas
    Canturk, Tayyar
    Turanl, Ahmet Y.
    PEDIATRIC DERMATOLOGY, 2011, 28 (03) : 306 - 312
  • [27] Multicenter case-control study of the risk factors for ulcerative colitis in China
    Wang, Yu-Fang
    Qin Ou-yang
    Xia, Bing
    Liu, Li-Na
    Gu, Fang
    Zhou, Kai-Fang
    Mei, Qiao
    Shi, Rui-Hua
    Ran, Zhi-Hua
    Wang, Xiao-Di
    Hu, Pin-Jin
    Wu, Kai-Chun
    Liu, Xin-Guang
    Miao, Ying-Lei
    Han, Ying
    Wu, Xiao-Ping
    He, Guo-Bing
    Zhong, Jie
    Liu, Guan-Jian
    WORLD JOURNAL OF GASTROENTEROLOGY, 2013, 19 (11) : 1827 - 1833
  • [28] Multicenter case-control study of the risk factors for ulcerative colitis in China
    Yu-Fang Wang
    Qin Ou-yang
    Bing Xia
    Li-Na Liu
    Fang Gu
    Kai-Fang Zhou
    Qiao Mei
    Rui-Hua Shi
    Zhi-Hua Ran
    Xiao-Di Wang
    Pin-Jin Hu
    Kai-Chun Wu
    Xin-Guang Liu
    Ying-Lei Miao
    Ying Han
    Xiao-Ping Wu
    Guo-Bing He
    Jie Zhong
    Guan-Jian Liu
    World Journal of Gastroenterology, 2013, (11) : 1827 - 1833
  • [29] RISK-FACTORS FOR ANTEPARTUM AND INTRAPARTUM STILLBIRTH
    LITTLE, RE
    WEINBERG, CR
    AMERICAN JOURNAL OF EPIDEMIOLOGY, 1993, 137 (11) : 1177 - 1189
  • [30] Risk factors for stillbirth and early neonatal death: a case-control study in tertiary hospitals in Addis Ababa, Ethiopia
    Eskinder Kebede
    Melani Kekulawala
    BMC Pregnancy and Childbirth, 21