Oral epithelial dysplasia: clinical characteristics of western European residents

被引:29
作者
Jaber, MA
Porter, SR
Speight, P
Eveson, JW
Scully, C
机构
[1] Univ London, UCL, Eastman Dent Inst Oral Hlth Care Sci, Dept Oral Med, London WC1X 8LD, England
[2] Univ London, UCL, Eastman Dent Inst Oral Hlth Care Sci, Dept Oral & Maxillofacial Pathol, London WC1X 8LD, England
[3] Univ Bristol, Sch Dent, Div Oral Med Pathol & Microbiol, Bristol BS1 2LY, Avon, England
关键词
clinical; histopathological; oral epithelial dysplasia; malignant; potentially malignant;
D O I
10.1016/S1368-8375(03)00045-9
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
To detail the clinical presentation of oral epithelial dysplasia in a large cohort of residents in western Europe. Descriptive statistical analysis of the data were calculated using chi-square and Fisher's exact tests. Oral epithelial dysplasia manifested typically as a white or mixed red and white lesion on the tongue, buccal mucosa or floor of mouth. The peak age of presentation of oral epithelial dysplasia was the 6th decade. Most clinically detected lesions had only mild oral epithelial dysplasia. Although uncommon, lesions with severe dysplasia were most likely to arise on the floor of mouth or lateral border of tongue. Oral epithelial dysplasia is likely to manifest as a solitary white patch, but it is not possible to accurately predict the likely degree of dysplasia from the clinical features of such lesions. (C) 2003 Elsevier Science Ltd. All rights reserved.
引用
收藏
页码:589 / 596
页数:8
相关论文
共 41 条
[1]   INTRAEXAMINER AND INTEREXAMINER RELIABILITY IN THE DIAGNOSIS OF ORAL EPITHELIAL DYSPLASIA [J].
ABBEY, LM ;
KAUGARS, GE ;
GUNSOLLEY, JC ;
BURNS, JC ;
PAGE, DG ;
SVIRSKY, JA ;
EISENBERG, E ;
KRUTCHKOFF, DJ ;
CUSHING, M .
ORAL SURGERY ORAL MEDICINE ORAL PATHOLOGY ORAL RADIOLOGY AND ENDODONTICS, 1995, 80 (02) :188-191
[2]   Oral white lesions with special reference to precancerous and tobacco related lesions: Conclusions of an international symposium held in Uppsala, Sweden, May 18-21 1994 [J].
Axell, T ;
Pindborg, JJ ;
Smith, CJ ;
vanderWaal, I .
JOURNAL OF ORAL PATHOLOGY & MEDICINE, 1996, 25 (02) :49-54
[3]   OCCURRENCE OF EPITHELIAL DYSPLASIA IN ORAL LEUKOPLAKIA [J].
BANOCZY, J ;
CSIBA, A .
ORAL SURGERY ORAL MEDICINE ORAL PATHOLOGY ORAL RADIOLOGY AND ENDODONTOLOGY, 1976, 42 (06) :766-774
[4]  
Banoczy J, 1972, J Oral Pathol, V1, P265, DOI 10.1111/j.1600-0714.1972.tb01665.x
[5]   SQUAMOUS-CELL CARCINOMA OF ORAL TONGUE IN PATIENTS LESS THAN 30 YEARS OF AGE [J].
BYERS, RM .
AMERICAN JOURNAL OF SURGERY, 1975, 130 (04) :475-478
[6]   Potentially malignant oval lesions in Northern Ireland: a 20-year population-based perspective of malignant transformation [J].
Cowan, CG ;
Gregg, TA ;
Napier, SS ;
McKenna, SM ;
Kee, F .
ORAL DISEASES, 2001, 7 (01) :18-24
[7]  
DEPUE RH, 1986, NEW ENGL J MED, V315, P647
[8]   TREATMENT OF AN ORAL ERYTHROPLASTIC SQUAMOUS-CELL CARCINOMA WITH MOHS MICROGRAPHIC SURGERY [J].
ELIEZRI, YD ;
ISRAEL, HA ;
POCHAL, WF .
ORAL SURGERY ORAL MEDICINE ORAL PATHOLOGY ORAL RADIOLOGY AND ENDODONTICS, 1989, 67 (03) :249-254
[9]  
Guo ZM, 2001, CLIN CANCER RES, V7, P1963
[10]  
GUPTA PC, 1989, CANCER-AM CANCER SOC, V63, P2247, DOI 10.1002/1097-0142(19890601)63:11<2247::AID-CNCR2820631132>3.0.CO