Iridium(I)-catalyzed asymmetric intermolecular hydroarylation of norbornene with benzamide

被引：69

作者：

Aufdenblatten, R ^{[1
]}

Diezi, S ^{[1
]}

Togni, A ^{[1
]}

机构：

[1] ETH Zentrum, Swiss Fed Inst Technol, Inorgan Chem Lab, CH-8092 Zurich, Switzerland

来源：

MONATSHEFTE FUR CHEMIE | 2000年 / 131卷 / 12期

关键词：

iridium; asymmetric catalysis; hydroarylation; hydroamination; norbornene;

D O I：

10.1007/s007060070014

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Starting from the dinuclear chloro-bridged Ir(I) complexes [IrCl(PP)](2) (PP=(R)-(6,6'-dimethylbiphenyl-2,2'-diyl)- 1, 1'-bis-(diphenylphosphine),and (R)-1-((S)-2-(diphenlyphosphino-ferrocenyl))-ethyldicyclohexyl-phosphine),a new class of cyclopentadienyl Ir(I) complexes containing a chiral bisphosphine ([IrCp(PP)]) was prepared and characterized. These new complexes are suited precatalysts for the direct hydroarylation of norbornene with benzamide. 2-(exo-Norbornyl)-benzamide is formed with an enantiomeric excess of up to 94% by the use of 1 mol% iridium, albeit in low yield.

引用

页码：1345 / 1350

页数：6

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