Study of antimicrobial effects of functionalized silver nanoparticles

被引：0

作者：

Popescu, Elena Leocadia ^{[1
]}

Balasoiu, Maria ^{[2
]}

Cristea, Oana Mariana ^{[2
]}

Stoica, Alexandra Elena ^{[3
]}

Oprea, Ovidiu Cristian ^{[4
]}

Vasile, Bogdan Stefan ^{[3
]}

Grumezescu, Alexandru Mihai ^{[3
]}

Bancescu, Gabriela ^{[5
]}

Busuioc, Cristina Jana ^{[6
]}

Mogosanu, George Dan ^{[7
]}

Streba, Costin Teodor ^{[8
]}

Mogoanta, Laurentiu ^{[6
]}

机构：

[1] Univ Med & Pharm Craiova, Doctoral Sch, Craiova, Romania

[2] Univ Med & Pharm Craiova, Dept Microbiol, Craiova, Romania

[3] Univ Politehn Bucuresti, Fac Appl Chem & Mat Sci, Dept Sci & Engn Oxide Mat & Nanomat, Bucharest, Romania

[4] Univ Politehn Bucuresti, Dept Inorgan Chem Phys Chem & Electrochem, Bucharest, Romania

[5] Carol Davila Univ Med & Pharm, Fac Dent Med, Dept Microbiol, Bucharest, Romania

[6] Univ Med & Pharm Craiova, Dept Histol, 2 Petru Rares St, Craiova 200349, Dolj County, Romania

[7] Univ Med & Pharm Craiova, Fac Pharm, Dept Pharmacognosy & Phytotherapy, Craiova, Romania

[8] Univ Med & Pharm Craiova, Dept Res Methodol, Craiova, Romania

来源：

ROMANIAN JOURNAL OF MORPHOLOGY AND EMBRYOLOGY | 2019年 / 60卷 / 03期

关键词：

multidrug resistance; antibiotics; silver nanoparticles; antibacterial agent; ESCHERICHIA-COLI; ANTIBACTERIAL ACTIVITY; OXIDE NANOPARTICLES; NANO SILVER; TOXICITY; MECHANISM; WORLDWIDE; EFFICACY; DELIVERY; AGENTS;

D O I：

暂无

中图分类号：

Q [生物科学];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

In recent decades, the study of nanoparticles (NPs) has gained a great scientific interest, due to a wide range of potential applications, in different fields: electronic, optical and biomedical. Some of the most studied effects of NPs are antibacterial ones, because the large, sometimes unjustified and uncontrolled administration of antibiotics has led to the emergence of multidrug-resistant (MDR) bacterial strains. In our study, starting from silver nitrate (AgNO3), we made approximately 30 nm spherical AgNPs that were coated with a thin layer of ethylene glycol (EG) or EG and polyvinylpyrrolidone (PVP). The microbial culture study showed that AgNPs have antibacterial effects, depending on the dose of the NPs and the type of bacteria.

引用

页码：939 / 946

页数：8

共 54 条

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