Reactions of dimethyl and di-tert-butyl 2-aryl-4-hydroxy-4-methyl-6-oxocyclohexane-1,3-dicarboxylates with difunctional nucleophiles

被引：8
|
作者：
Gein, VL [1 ]
Gein, NV
Potemkin, KD
Kriven'ko, AP
机构：
[1] Perm State Pharmaceut Acad, Perm, Russia
[2] Saratov NG Chernyshevskii State Univ, Saratov, Russia
来源：
RUSSIAN JOURNAL OF GENERAL CHEMISTRY | 2004年 / 74卷 / 10期
基金：
俄罗斯基础研究基金会;
关键词：
Ester; Hydrate; Dimethyl; Hydrazine; Alkyl Group;
D O I：
10.1007/s11176-005-0056-x
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
The nature of the alkyl group in the ester moieties of dimethyl and di-tert-butyl 2-aryl-4-hydroxy-4-methyl-6-oxocyclohexane-1,3-dicarboxylates affects the direction of their reactions with difunctional nucleophiles. The dimethyl esters react with hydrazine hydrate to give the corresponding tetrahydroindazoles, while their tert-butyl analogs are converted under similar conditions into 6-hydrazones. Reactions of both dimethyl and di-tert-butyl 6-oxocyclohexane-1,3-dicarboxylates with hydroxylamine lead to formation of 6-hydroxyimino derivatives.
引用
收藏
页码：1564 / 1568
页数：5
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